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This combination medication contains antidyskinetic drugs, prescribed for Parkinson’s disease.  The addition of Carbidopa enhances lower dose of Levodopa to be used.

Drug information on Duodopa (100 mg) (Carbidopa-Levodopa) from Wockhardt Limited (Merind)

Duodopa (100 mg)

Wockhardt Limited (Merind)
Generic : Carbidopa-Levodopa
10 Tablets
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Medical Condition(s) for which Duodopa (100 mg) may be prescribed

Side effects of Duodopa (100 mg)

   Most common : Involuntary movements and nausea.

   Body as a Whole : Chest pain and weakness.

   Heart : Irregular heart beat, low/high blood pressure, fainting, vein inflammation and palpitations.

   Gastrointestinal : Dark saliva, stomach bleeding, development of duodenal ulcer, loss of appetite, vomiting, diarrhea, constipation, indigestion, dry mouth and taste alterations.

   Blood : Anemia, decrease in white blood cells and platelets.

   Hypersensitivity : Shock, hives, itching, bruising and lesions.

   Musculoskeletal : Back pain, shoulder pain and muscle cramps.

   Central Nervous System: Hallucinations, confusion, agitation, dizziness, drowsiness, abnormal dreams, sleeplessness, tingling, headache, depression, suicidal tendencies, dementia and increased sexual drive.

   Respiratory : Difficulty in breathing and upper respiratory infection.

   Skin : Rash, increased sweating, hair loss and increased sweating.

   Genitourinary : Urinary tract infection, urinary frequency and dark colored urine.

Dosage & When it is to be taken (Indications)

Initial: Adult- PO- Per tab contains L-dopa 100 mg and carbidopa 25 mg. Initial: 1 tab 3 times per day. It may be increased.

How to use Duodopa (100 mg)?

It comes as a capsule and tablet to take by mouth, on an empty stomach.

When is Duodopa (100 mg) not to be taken? (Contraindications)

Contraindicated in patients with skin lesions or cancer, co-administration with MAOIs or within 14 days of MAOIs administration and hypersensitivity.

Warnings and Precautions for Duodopa (100 mg)

Caution should be exercised in patients with history of hormone problems, asthma, mental illness, diabetes, ulcer, heart attack, irregular heartbeat, heart, kidney, liver or lung disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breast feeding.

• It may cause drowsiness, dizziness or lightheadedness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• It may cause mental or mood changes; if it is so consult with your doctor.

• Patient may develop with increased risk of Neuroleptic Malignant Syndrome with the following symptoms: fever, stiff muscles, confusion, abnormal thinking, fast or irregular heartbeat and sweating. If it is so consult with your doctor.

• Monitor complete blood cell counts and liver function regularly while taking this medication.

Other Precautions for Duodopa (100 mg)

Avoid excess dosage.

Storage Conditions for Duodopa (100 mg)

Store it at room temperature, away from direct sunlight and excess heat and moisture.

Schedule : H  Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

Disclaimer : The Price of the drugs indicated above may not match the actual price at which they are sold. Prices can change depending on many factors, including GST. These are only approximate indicative prices of the drug.
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