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Drug information on Foliglo (Biotin) from Glenmark Pharmaceuticals Ltd. (Gracewell)

Foliglo   Capsule Glenmark Pharmaceuticals Ltd. (Gracewell) Generic : Biotin	95.00 20mg / 10IU / 5mg / 1.7mg / 1.5mg / 300mcg / 300mcg / 15mg / 50mcg / 6mg 10

Written & Compiled by Pharmacist Vijayaganesh Kasinathan, B.Pharm, M.Pharm

Medically Reviewed by Dr. Simi Paknikar, MD

Last Updated on Dec 06, 2017

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Vitamin Supplements

Biotin is a water-soluble B - complex vitamin which is used as a nutrition supplement either alone or in combination with other vitamins and minerals.
Biotin was co-discovered by Dean Burk, an American Biochemist.

• Biotin is usually safe and very well-tolerated.

• Adverse effects include allergic reactions or mild upset stomach.

• Skin reactions such as urticaria, itchiness, redness or pain at injection site may occur after the administration of injections.

The recommended daily intake of biotin in the diet include the following:

• Infants (0 to 12 months) : 7mcg

• Children
(1 to 3 years) : 8mcg
(4 to 8 years) : 12mcg
(9 to 13 years) : 20mcg
(14 to 18 years) : 25mcg

• Adults over 18 years and pregnant women: 30mcg

• Breastfeeding women: 35mcg

• Biotin comes in a tablet or capsule or syrup form to be taken by mouth with food.
• Patients who consume raw egg whites for several months and patients on parenteral nutrition treatment may require biotin injections given intravenously.
• Biotin injections are also available for intramuscular administration.

Biotin is not recommended:
• In patients with unusual or allergic reactions to biotin supplements
• In children, or pregnant or breastfeeding women without the physician’s advice

• Smoking should be avoided as it may increase the metabolism of biotin in the body.
• Patients who undergo dialysis may require high dose which should be evaluated by the medical specialist.
• Biotin requirements must be tailored according to the needs of the required individual such as burn patients, athletes, epileptics, elderly patients, gastrectomy (partial or total surgical removal of stomach) and in achlorhydria (production of acid in the stomach is absent) which needs medical judgement.

• Regular long-term consumption of raw egg white should be avoided as it binds and reduces the absorption of biotin in the body.
• Taking biotin-rich foods such as egg yolks, avocados, cauliflower, whole grains, pork, liver, salmon fish and fruits such as raspberries can help to recover faster from deficiency.

• Concentrations of biotin in the blood may be altered when taken along with medicines such as phenobarbitone, phenytoin, primidone, carbamazepine or some antibiotics.
• The concentrations of drugs like imipramine, fluvoxamine, haloperidol, olanzapine, clozapine, propranolol, and theophylline may be altered by biotin.
• Dietary supplements such as alpha-lipoic acid and pantothenic acid or vitamin B5 taken together with biotin decreases the absorption of each other and the combination should be avoided.

• Store at room temperature (20-25°C) and keep away from excess heat and moisture.