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Drug information on Macpee (25 mg) (Bethanechol) from Intas Pharmaceutical Ltd.

Macpee (25 mg)

Intas Pharmaceutical Ltd.
Generic : Bethanechol
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Drug Name : Bethanechol

Bethanechol(Urecholine) generic Bethanechol is a powerful cholinergic agent. It stimulates the bladder muscle to improve the urine flow and thereby helps in emptying the bladder. It is used for the treatment of urinary retention without any structural obstruction. Bethanechol is sometimes prescribed by the doctor for abdominal distension due to dilated colon and in the treatment of gastroesophageal reflux disease, in which the acid from the stomach moves back to the esophagus or foodpipe.
More Info about Bethanechol

Other Trade Names for Bethanechol

Madhumathi Palaniappan
Written & Compiled by Madhumathi Palaniappan, B.Pharm
Medically Reviewed by The Medindia Medical Review Team on May 31, 2016

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Medical Condition(s) for which Macpee (25 mg) may be prescribed

Side effects of Macpee (25 mg)

  Gastrointestinal - Nausea, vomiting, belching, increased salivation, abdominal cramps and diarrhea.

  Genitourinary - Frequent urge to urinate.

  Respiratory - Difficulty in breathing, precipitation of asthmatic attacks.

  Central Nervous System:Dizziness, light headedness, headache.

  Heart: Low blood pressure with fast heart rate, feeling faint.

  Eye: Watering of eyes, problems with vision.

  Skin – Flushing of skin due to dilatation of blood vessels, sweating, rashes in case of allergy.

Dosage & When it is to be taken (Indications)

Adult: The recommended oral dose is 10-50 mg 3-4 times/day. It is also given in the form of subcutaneous (under the skin) injection by administering a dose of 5 mg 3-4 times/day. The dose is fixed based on the type and severity of the condition to be treated.

How to use Macpee (25 mg)?

It comes as a tablet to be taken by mouth with a full glass of water. It should be taken on an empty stomach one hour before meals or two hours after meals to avoid nausea and vomiting. It is also available as an elixir and solution for injection.

When is Macpee (25 mg) not to be taken? (Contraindications)

Bethanechol is contraindicated in patients who are allergic to the drug, with history of asthma, peptic ulcer, intestinal or urinary obstruction, following recent gastrointestinal or urinary surgery, decreased heart rate and low blood pressure, epilepsy, Parkinsonism, coronary heart disease and overactive thyroid.

Warnings and Precautions for Macpee (25 mg)

Caution should be exercised in patients with history of chronic obstructive pulmonary disease (COPD), low blood pressure, slow heart rate, prostate enlargement, who are taking other medications, any allergy, elderly and in children.

• Bethanechol should be avoided during pregnancy.

• Avoid driving a car or operating machinery, and get up slowly from bed while taking this medication as this medicine may cause dizziness and light headedness.

• Avoid alcohol consumption.

Other Precautions for Macpee (25 mg)

Avoid excess dosage.
Consult the doctor immediately if any serious adverse effects occur like tightness in the chest or difficulty with breathing.

Drug Interactions of Macpee (25 mg)

Bethanechol should be avoided with:
Ganglion blocking compounds as it can cause severe lowering of blood pressure.
Drugs which are used for the treatment of Alzheimer’s disease like donepezil, tacrine due to the additive side effects like increased saliva, bowel movements, blurred vision and urination.

Storage Conditions for Macpee (25 mg)

Store it in a closed container at room temperature. Protect from heat, light and excess moisture. Keep away from children.

Disclaimer : updates the prices regularly, however despite that there may be discrepancies in the prices displayed. This can be due to many reasons including -
  • Difference in GST/local taxes
  • Change in price by the company
  • Updation of information may not have happened at the right time
For the above reasons Medindia cannot be held liable for any action taken based on the information provided by its website. The purpose of this website is to only provide the initial guidance and it does not intend to replace professional medical opinion in any manner whatsoever.

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