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Drug information on Zymurine (50 mg) (Azathioprine) from Zydus Cadila Healthcare Ltd. (Biogen)

Zymurine (50 mg)

Zydus Cadila Healthcare Ltd. (Biogen)
Generic : Azathioprine
10 Tablets
Dhanalakshmi Chinnuswamy
Further Checked by The Medindia Medical Review Team on February, 2, 2017
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Medical Condition(s) for which Zymurine (50 mg) may be prescribed

Side effects of Zymurine (50 mg)

   Blood : Decreased white blood cells and platelets.

   Gastrointestinal : Nausea, vomiting, diarrhea and abdominal pain.

   Miscellaneous : Rash, hair loss, fever, joint pain, diarrhea, negative nitrogen balance and reversible interstitial lung inflammation.

Dosage & When it is to be taken (Indications)

Adult: PO- Rheumatoid arthritis Initial: 1 mg/kg/day for 6-8 wk. May adjust dose gradually to 2.5 mg/kg/day if needed.
Prevention of rejection in organ and tissue transplantation -1-5 mg/kg/day.
Auto-immune diseases -1-3 mg/kg/day.
IV -Renal homotransplantation- Usual initial: 3-5 mg/kg/day beginning at the time of transplantation. Maintenance: 1-3 mg/kg/day.

How to use Zymurine (50 mg)?

It comes as a tablet to take by mouth, with food.

When is Zymurine (50 mg) not to be taken? (Contraindications)

Contraindicated in patients with known hypersensitivity, previous treatment with alkylating agents, pregnancy and breastfeeding.

Warnings and Precautions for Zymurine (50 mg)

Caution should be exercised in patients with history of kidney or liver problems, gout, any infection, anemia, bone marrow depression, any allergy, who are taking other medications and children.

• Avoid contact with people with infections.

• It may reduce platelet counts; avoid injury or bruising.

• Patient may experience severe nausea and vomiting; if it so consult with your doctor.

• Patient may develop with increased risk of cancer; if you notice any unusual growth or tumor consult with your doctor immediately.

Other Precautions for Zymurine (50 mg)

Monitor complete blood counts, liver function, and TPMT enzyme activity, while taking this medication.
Avoid excess dosage.

Storage Conditions for Zymurine (50 mg)

Store it at room temperature and in an airtight container, keep away from children.

Schedule : H  Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

Disclaimer : Change in the rate of medication is possible and the rates shown maybe more or less than the rate displayed due to added GST and pricing changes made by the companies.
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