Zymurine (50 mg) is an immunosuppressant, prescribed for prevention of rejection kidney transplantation. It is also used for rheumatoid arthritis and autoimmune diseases.
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Drug information on Zymurine (50 mg) (Azathioprine) from Zydus Cadila Healthcare Ltd. (Biogen)
Drug Name : Azathioprine
Azathioprine(Azasan and Imuran) generic Zymurine (50 mg) is an immunosuppressant, prescribed for prevention of rejection kidney transplantation. It is also used for rheumatoid arthritis and autoimmune diseases.
More Info about Azathioprine
Trade Names for Azathioprine
Azasan and Imuran
Adult: PO- Rheumatoid arthritis Initial: 1 mg/kg/day for 6-8 wk. May adjust dose gradually to 2.5 mg/kg/day if needed.
Prevention of rejection in organ and tissue transplantation -1-5 mg/kg/day.
Auto-immune diseases -1-3 mg/kg/day.
IV -Renal homotransplantation- Usual initial: 3-5 mg/kg/day beginning at the time of transplantation. Maintenance: 1-3 mg/kg/day.
Decreased white blood cells and platelets.
Nausea, vomiting, diarrhea and abdominal pain.
Rash, hair loss, fever, joint pain, diarrhea, negative nitrogen balance and reversible interstitial lung inflammation.
It comes as a tablet to take by mouth, with food.
Contraindicated in patients with known hypersensitivity, previous treatment with alkylating agents, pregnancy and breastfeeding.
Caution should be exercised in patients with history of kidney or liver problems, gout, any infection, anemia, bone marrow depression, any allergy, who are taking other medications and children.
Avoid contact with people with infections.
It may reduce platelet counts; avoid injury or bruising.
Patient may experience severe nausea and vomiting; if it so consult with your doctor.
Patient may develop with increased risk of cancer; if you notice any unusual growth or tumor consult with your doctor immediately.
Monitor complete blood counts, liver function, and TPMT enzyme activity, while taking this medication.
Avoid excess dosage.
Store it at room temperature and in an airtight container, keep away from children.
Schedule : H Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.