Zymurine (Azathioprine) Drug Price and Information

Azathioprine (Zymurine) is an immunosuppressant, prescribed for prevention of rejection kidney transplantation. It is also used for rheumatoid arthritis and autoimmune diseases. 
The information provided on this page is intended to serve as a comprehensive resource and should not be a substitute to professional medical advice. If you have concerns it is always best to speak with a healthcare professional.

Zymurine - Cadila Healthcare Ltd

Zymurine  Tablet

Generic : Azathioprine
Price Updated on Aug 07, 2023
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Substitute/Alternative Medication to Zymurine
Aprin , Azap (50 mg) , Azimune , Thiazprine (50 mg) , Transimune (50 mg)

Drug information on Zymurine from Cadila Healthcare Ltd


When is Zymurine prescribed?

It is prescribed for -

What should be the dose and frequency?

Adult: PO- Rheumatoid arthritis Initial: 1 mg/kg/day for 6-8 wk. May adjust dose gradually to 2.5 mg/kg/day if needed.
Prevention of rejection in organ and tissue transplantation -1-5 mg/kg/day.
Auto-immune diseases -1-3 mg/kg/day.
IV -Renal homotransplantation- Usual initial: 3-5 mg/kg/day beginning at the time of transplantation. Maintenance: 1-3 mg/kg/day.

What are the common side effects of Zymurine

Blood : Decreased white blood cells and platelets.

Gastrointestinal : Nausea, vomiting, diarrhea and abdominal pain.

Miscellaneous : Rash, hair loss, fever, joint pain, diarrhea, negative nitrogen balance and reversible interstitial lung inflammation.

How to use Zymurine?

It comes as a tablet to take by mouth, with food.


In which conditions should Zymurine be avoided?

Contraindicated in patients with known hypersensitivity, previous treatment with alkylating agents, pregnancy and breastfeeding.


What are the Precautions needed with Zymurine

Caution should be exercised in patients with history of kidney or liver problems, gout, any infection, anemia, bone marrow depression, any allergy, who are taking other medications and children.

Avoid contact with people with infections.

It may reduce platelet counts; avoid injury or bruising.

Patient may experience severe nausea and vomiting; if it so consult with your doctor.

Patient may develop with increased risk of cancer; if you notice any unusual growth or tumor consult with your doctor immediately.

Are there any additional Precautions?

Monitor complete blood counts, liver function, and TPMT enzyme activity, while taking this medication.
Avoid excess dosage.

At What Temperature Should it be Stored?

Store it at room temperature and in an airtight container, keep away from children.

Schedule : H  Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

Azathioprine: Immunosuppressant For Kidney Transplant Rejection and to Treat Rheumatoid Arthritis

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