Atorvastatin (Zestat FC) is an HMG-CoA reductase inhibitor, also known as "statin”, prescribed for hyperlipidemia.
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Adult PO- Initial- The recommended dose is 10 mg daily. Maximum: 80 mg/day.
What are the common side effects of Zestat FC
Most Common : Nose inflammation, joint pain, diarrhea, pain in extremity, urinary tract infection, indigestion, nausea, muscle and bone pain, muscle spasms, sleeplessness and throat pain.
Body as a whole : Uneasiness and fever.
Gastrointestinal : Abdominal discomfort, eructation, flatulence, liver inflammation and bile obstruction.
Musculoskeletal : Muscle fatigue, neck pain and joint swelling.
Metabolic : Increase in liver enzymes level, abnormal liver function tests and increased sugar level.
Central Nervous system : Dizziness, depression, fatigue, peripheral neuropathy and abnormal dreams.
Respiratory : Nose bleed.
Skin : Hives.
Eye and ENT : Blurred vision and ringing in the ear.
It comes as a tablet to take by mouth, with or without food.
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In which conditions should Zestat FC be avoided?
Contraindicated in patients with severe liver problems, who are taking HIV protease inhibitors, during pregnancy and breastfeeding, and hypersensitivity.
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What are the Precautions needed with Zestat FC
Caution should be exercised in patients with history of low blood pressure, serious infection, seizures, electrolyte problems, liver problems, alcohol abuse, any allergy, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.
Follow the diet and exercise program as directed by your physician.
Monitor blood cholesterol level and liver functions regularly while taking this medication.
Are there any additional Precautions?
Avoid excess dosage.
At What Temperature Should it be Stored?
Store it at room temperature (25°C).
Atorvastatin: Know More About The Cholesterol Lowering Drug
A: Zestat FC is not recommended for patients with hypersensitivity to the drug, acute liver disease, non-alcoholic fatty liver disease and hepatitis(1✔✔Trusted Source Atorvastatin
A: Zestat FC is not recommended during pregnancy or in women who may become pregnant. Statins are not recommended during pregnancy due to the increased risk of congenital abnormalities in the fetus(2✔✔Trusted Source Statin use during pregnancy: a systematic review and meta-analysis
A:Avoid grapefruit juice while taking Zestat FC, as it significantly affects the pharmacokinetics of Zestat FC. Concurrent use of Zestat FC and st john's wort may reduce Zestat FC effectiveness(3✔✔Trusted Source Effects of grapefruit juice on pharmacokinetics of atorvastatin and pravastatin in Japanese
Q: Is it better to take Zestat FC at night or morning?
A: It is usually taken once a day, either in the morning or evening, with or without food. It is better to take Zestat FC around the same time every day(4✔✔Trusted Source Atorvastatin
A: The long term use of Zestat FC is safe and effective in the treatment of hypercholesterolaemia. Do not discontinue the medication without consulting your doctor(5✔✔Trusted Source Long-term efficacy and safety of a generic atorvastatin in usual clinical care setting
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2. Statin use during pregnancy: a systematic review and meta-analysis - ( https://pubmed.ncbi.nlm.nih.gov/22390808/)
3. Effects of grapefruit juice on pharmacokinetics of atorvastatin and pravastatin in Japanese - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884469/ )
5. Long-term efficacy and safety of a generic atorvastatin in usual clinical care setting - (https://pubmed.ncbi.nlm.nih.gov/22111443/ )
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