Vijayaganesh Kasinathan
Written & Compiled by Pharmacist Vijayaganesh Kasinathan, B.Pharm, M.Pharm
Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
Last Updated on Oct 07, 2017
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General Information on Zaltoprofen

Generic Name : Zaltoprofen

Latest prescription information about Zaltoprofen. Learn its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Anti- Inflammatory Agents

Trade Names/Brand Names of Zaltoprofen

India : 

Overview of Zaltoprofen

Zaltoprofen is an effective propionic acid derivative (similar to Ibuprofen molecule) NSAID (Non-Steroidal Anti-Inflammatory Drug) which is used to treat various pain, musculoskeletal and joint disorders.

Why is Zaltoprofen Prescribed? (Indications)

Zaltoprofen is a nonsteroidal anti-inflammatory drug. It is a preferential COX-2 inhibitor which selectively inhibits the production of prostaglandin E2 (a physiologically active biological compound) at inflammatory sites and therefore reduces pain and inflammation. In addition, it inhibits bradykinin-(an agent that mediates pain and inflammation) induced pain responses.

Zaltoprofen is prescribed for treating pain and inflammatory conditions caused by various disorders such as dental pain, musculoskeletal pain, post-operative pain, lumbar pain, frozen shoulder, osteoarthritis and cervicobrachial syndrome.  

When should Zaltoprofen not to be taken? (Contraindications)

Zaltoprofen should not be given to patients with:

Peptic ulcer with or without a rupture in the gastrointestinal tract as the NSAID group causes gastrointestinal bleeding.
Ulcerative colitis or Crohn's disease (inflammatory bowel disease)
Blood abnormalities
Cardiovascular disease as some cardiovascular deaths have been noted with some NSAIDs.
Asthma, since it could cause an asthmatic attack.
Allergy to the drug
Severe liver or kidney damage

What is the dosage of Zaltoprofen?

For the treatment of arthritis-related and other pain conditions:
The recommended adult dose is 80mg three times daily.

How should Zaltoprofen be taken?

Zaltoprofen comes as a tablet to be taken by mouth.
It should be taken with food to avoid gastric discomfort.

What are the warnings and precautions for Zaltoprofen?

Zaltoprofen should not be used in children, pregnant women and breastfeeding mothers because of the lack of safety and effectiveness data.

What are the side effects of Zaltoprofen?

  Gastrointestinal: Loss of appetite, nausea, vomiting, dry mouth, gastric irritation and constipation
  Central Nervous System: Drowsiness, feeling of numbness and dizziness
  Skin: Sensitivity to light and itching
  Blood: Low red blood cell count and increased platelet count
  Others: Increased frequency of urination, blood in urine, pain on urination, rise in liver enzymes or creatinine level, fever

What are the other precautions for Zaltoprofen?

In case of overdosage, the patient should be treated symptomatically for complications such as hypotension (decrease in blood pressure), gastrointestinal irritation, kidney damage and breathing difficulties.

What are the Drug Interactions of Zaltoprofen?

Anticoagulants: Zaltoprofen may increase the anticoagulant effects of drugs such as warfarin and heparin.
Quinolones: Concomitant of quinolone antibacterials such as ciprofloxacin and nalidixic acid with zaltoprofen may result in convulsions.
Antidiabetics: Zaltoprofen taken together with sulfonylurea drugs such as chlorpropamide, glipizide and gliclazide may increase the hypoglycemic action of antidiabetic drugs.
Lithium: The dose of lithium may have to be adjusted with zaltoprofen because of the increased effects of lithium with zaltoprofen.

What are the storage conditions for Zaltoprofen?

Store at room temperature.
Protect from heat and moisture.
Keep out of reach of children.

Last Updated : 10/7/2017

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