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Varenicline - Indications, Dosage, Side Effects and Precautions

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Information about Varenicline

Generic Name : Varenicline
Pronunciation : var-EN-i-kleen
Latest prescription information about Varenicline. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Smoking Cessation Agent
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Trade Names/Brand Names of Varenicline

India : 

International : 

Chantix
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Why is Varenicline Prescribed? (Indications)

This medication is a nicotinic receptor partial agonist, prescribed for smoking cessation.  It blocks the pleasant effects of nicotine (from smoking) on the brain.
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When should Varenicline not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Varenicline?

Adult: PO- 0.5 mg once daily for 1st 3 days, followed by 0.5 mg twice daily for the next 4 days. Maintenance (week 2-12): 1 mg twice daily.
Initiate dose 1-2 week before target quit date. Usual treatment duration: 12 weeks.
May continue for another 12 weeks to reduce relapse in patients who have successfully quit after the initial treatment course.

How should Varenicline be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Varenicline?

• Caution should be exercised in patients with history of kidney problems or dialysis, mental or mood problems, suicidal thoughts, who are taking other medication, any allergy, elderly, during pregnancy and breastfeeding.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

Patient may develop with elevated mood or changes in behavior and Suicidality; if it so consult with your doctor.

What are the side effects of Varenicline?

  Gastrointestinal : Nausea, vomiting, abdominal pain, flatulence, indigestion, gastrointestinal motility/defecation conditions, constipation, acid reflux disease, salivary gland conditions and dry mouth.
  Central Nervous System : Sleep disorder/disturbances, sleeplessness, abnormal dreams, negative emotional state, headache, nerve disorders, drowsiness and abnormal taste.
  General : Fatigue/uneasiness/weakness.
  Respiratory : Runny nose, difficulty in breathing and upper respiratory tract disorder.
  Skin : Rash and itching.
  Metabolic : Increased and decreased appetite.
  Heart: Chest pain, peripheral vascular disease (PVD).

What are the other precautions for Varenicline?

Monitor kidney and liver functions regularly while taking this medication.

What are the storage conditions for Varenicline?

Store it at room temperature and in an airtight container. Keep away from children.



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