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Trimethadione - Indications, Dosage, Side Effects and Precautions

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Information about Trimethadione

Generic Name : Trimethadione
Up-to-date prescription details regarding Trimethadione are provided here.

Pronunciation : trye- meth- a- dye'- one

Learn the correct pronunciation of the Trimethadione, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y46.6 Therapeutic Classification : Anticonvulsants

Trade Names/Brand Names of Trimethadione

International :


Troxidone, Tridione

Why is Trimethadione Prescribed? (Indications)

This medication is an anticonvulsant, prescribed for seizure disorders.  It works by reducing abnormal electrical activity in the brain.

When should Trimethadione not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Trimethadione?

Adult - The recommended dose is 0.9-2.4 grams daily in 3 or 4 equally divided doses (i.e., 300-600 mg 3 or 4 times daily).
Children- Usually 0.3-0.9 gram daily in 3 or 4 equally divided doses.

How should Trimethadione be taken?

It comes as a tablet, capsule, and liquid to take by mouth on an empty stomach.

What are the warnings and precautions for Trimethadione?

• Caution should be exercised in patients with history of kidney, liver disease, blood disorders, eye problems, allergies, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

• Avoid exposure to sunlight.

What are the side effects of Trimethadione?

Gastrointestinal- Nausea, vomiting, abdominal pain, gastric distress.
Central Nervous System- Drowsiness, fatigue, uneasiness, sleeplessness, vertigo, headache, tingling, precipitation of grand mal seizures, increased irritability, personality changes.
Blood- Bleeding gums, epistaxis, retinal and petechial bleeding, vaginal bleeding, anemia, decrease in white blood cells, platelets; eosinophilia, and bone marrow depression.
Skin- Skin rash, skin inflammation, and redness.
Miscellaneous- Hiccups, loss of appetite, weight loss, hair loss, changes in blood pressure, albumin in urine, sensitivity to light, and double vision.

What are the other precautions for Trimethadione?

Avoid excess dosage.

What are the storage conditions for Trimethadione?

Store it at room temperature, away from excess heat and moisture.
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