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General Information on Trandolapril

Generic Name : Trandolapril

Pronunciation : tran dole' a pril

Latest prescription information about Trandolapril. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y52.4 | Therapeutic Classification : Anti- Hypertensives

Trade Names/Brand Names of Trandolapril

India : 

International : 

Mavik, Zetpril Tab

Why is Trandolapril Prescribed? (Indications)

This medication is an angiotensin-converting enzyme (ACE) inhibitor, prescribed for high blood pressure either alone or with other medications. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. This medication is also used to improve survival after an acute heart attack and with other drugs (e.g., diuretics, digoxin) to treat congestive heart failure.  

When should Trandolapril not to be taken? (Contraindications)

Hypersensitivity, last 6 months of pregnancy.
It should not be co-administered with antidiabetic medicines.

What is the dosage of Trandolapril?

PO- Hypertension- Adult: Initially, 0.5 mg once daily. First dose preferably given at bedtime. Maintenance: 1-2 mg once daily. Max: 4 mg daily in 1-2 divided doses.
In patients with co-existing heart failure, start treatment under close medical supervision.
PO- Heart failure after a heart attack- Adult: Initially, 0.5 mg once daily, may increase dose gradually to a target dose of 4 mg once daily. Patient may continue at the max tolerated dose if patient is unable to tolerate 4 mg/day dose.

How should Trandolapril be taken?

It comes as a tablet to take by mouth (orally), once or twice a day with or with out food.

What are the warnings and precautions for Trandolapril?

Caution should be exercised in patients with history of kidney disease, liver disease, high blood levels of potassium, heart problems, severe dehydration ,diabetes, strokes, autoimmune diseases, pregnancy and breastfeeding.

Drink adequate fluids to prevent from becoming dehydrated.

It may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. Get up slowly from bed.

It may lead to development of a serious adverse effect in which the patient experiences rapid swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or unusual hoarseness.

What are the side effects of Trandolapril?

  Heart: Low blood pressure, slow heart rate, poor blood supply, intermittent claudication ( reduced blood flow to the legs, stroke).
  Central Nervous System: Dizziness, lightheadedness, loss of consciousness.
  Gastrointestinal: Stomach upset, diarrhea.

  Metabolic: Increase in potassium, decrease in calcium in blood.
  Musculoskeletal: Muscle pain.
  Respiratory: Cough.
  Miscellaneous: Anaphylactoid reactions (allergic reaction include: rash, itching, swelling (especially of the face, lips, tongue, or throat), trouble breathing.

What are the other precautions for Trandolapril?

It may increase blood sugar; diabetes patients should monitor their blood glucose level regularly.

What are the storage conditions for Trandolapril?

Keep this medication in an airtight container, and away from children. Store it at room temperature.

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