This medication is a non-steroidal anti-inflammatory drug, prescribed for rheumatoid arthritis, osteoarthritis or juvenile arthritis. It blocks certain substances in the body that cause inflammation.
Contraindicated in patients who have experienced asthma, allergic reactions after taking aspirin or other NSAIDs and known hypersensitivity.
Rheumatoid arthritis or osteoarthritis- The recommended starting dose for adults is 400 mg three times daily (1200 mg daily).
Juvenile rheumatoid arthritis- The recommended starting dose for pediatric patients (2 years and older) is 20 mg/kg/day in divided doses.
It comes as a tablet and capsule to take by mouth, on an empty stomach.
• Caution should be exercised in patients with history of asthma, runny nose, swelling of the hands, feet, ankles or lower legs, heart, liver or kidney disease, high blood pressure, blood disorders, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
• Avoid alcohol consumption or smoking; otherwise it may cause severe bleeding in stomach or ulcer.
• Monitor kidney function, complete blood cell counts and blood pressure regularly while taking this medication.
• Gastrointestinal :
Nausea, indigestion, gastrointestinal distress, abdominal pain, diarrhea, flatulence, vomiting, constipation, stomach inflammation and peptic ulcer.
• Body as a Whole : Headache, weakness and chest pain.
• Heart : Elevated blood pressure and swelling.
• Central Nervous System : Dizziness, drowsiness and depression.
• Metabolic : Weight gain/ loss.
• Skin : Skin irritation.
• Eye and ENT : Ringing in the ear, and visual disturbances.
• Blood : Anemia.
• Genitourinary : Elevated BUN and urinary tract infection.
Avoid excess dosage.
Store it at controlled room temperature (15°-30°C), and in an airtight container. Keep away from children.
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