Information about Ticarcillin

Generic Name : Ticarcillin
Up-to-date prescription details regarding Ticarcillin are provided here.

Pronunciation : TYE-kar-SIL-in

Learn the correct pronunciation of the Ticarcillin, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y41.8 Therapeutic Classification : Anti- Infectives

Trade Names/Brand Names of Ticarcillin

India :

Timentin

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International :

Ticarnic Vial, Ticar

Why is Ticarcillin Prescribed? (Indications)

This medication is a penicillin antibiotic, prescribed for infections caused by certain bacteria. It blocks the growth of the bacteria's cell wall, resulting in the death of the bacteria.

When should Ticarcillin not be taken? (Contraindications)

Hypersensitivity to penicillins.

What is the dosage of Ticarcillin?

IV- Susceptible infections- The recommended dose is 200-300 mg/kg/day in divided doses 4 or 6 hourly.
Complicated UTI- The recommended dose is 150-200 mg/kg/day in divided doses 4 or 6 hourly.
IV/IM- Uncomplicated UTI- The recommended dose is 1 gm 6 hourly.

How should Ticarcillin be taken?

It comes as a solution to be injected (Intravenous/Intramuscular) by a doctor or hospital staff.

What are the warnings and precautions for Ticarcillin?

•Caution should be exercised in patients with history of asthma; hay fever; or kidney, liver, or gastrointestinal disease (especially colitis), during pregnancy and breastfeeding.

Monitor urine sugar regularly in diabetes patients, avoid using clinitest tablets.

It may lead to poor renal function (risk of neurotoxicity) or heart failure.

Avoid contact, skin sensitization may occur.

• Monitor electrolyte concentrations, kidney, liver and blood status during prolonged and high dose therapy.

Jarisch-Herxheimer reaction (death of bacteria) may be seen in spirochete infections particularly syphilis; Avoid intrathecal route.

What are the side effects of Ticarcillin?

Heart- Deep vein thrombosis, inflammation of vein, vein irritation.
Central Nervous System- Neurotoxicity-alters the normal activity of the nervous (eg, lethargy, neuromuscular irritability, hallucinations, convulsions, seizures).
Skin- Itching, rash, hives.
Eye- Itchy eyes.
Gastrointestinal- Diarrhea or bloody diarrhea, nausea, antibiotic-associated diarrhea(AAD), vomiting.
Genitourinary- Elevated creatinine or Blood Urea Nitrogen, inflammation of vagina.
Blood- Anemia, bone marrow depression, increase in eosinophils, platelets, excessive bleeding.
Liver- Transient hepatitis (elevated AST and ALT).
Metabolic- Elevated serum alkaline phosphatase, increased sodium and reduced potassium level in the blood.
Miscellaneous- Fever, blood clot, hypersensitivity reactions, pain at site of injection.