This medication is a chemotherapy agent, prescribed for ovary or breast cancer. It works by killing cancer cells.
Contraindicated in patients with liver, kidney disease, bone marrow depression and hypersensitivity.
Breast and Ovarian Carcinoma: Adults- IV- 0.3 to 0.4 mg/kg every 1 to 4 week. Alternative regimens- 0.2 mg/kg/day for 4 to 5 days every 2 to 4 week; or 6 mg/m 2 /day for 4 to 5 days every 2 to 4 week.
It comes as a solution for injection to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of kidney or liver problems, bone marrow problems, agranulocytosis, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.
• It may reduce platelet counts, avoid injury or bruising.
• Avoid live vaccination.
• General :
Fatigue and weakness.
• Hypersensitivity : Allergic reactions - rash, hives, laryngeal edema, asthma, shock and wheezing.
• Local : Skin inflammation and pain at the injection site.
• Gastrointestinal : Nausea, vomiting, abdominal pain and loss of appetite.
• Genitourinary : Painful urination and urinary retention.
• Respiratory : Difficulty in breathing.
• Central Nervous System : Dizziness, headache and blurred vision.
• Skin : Hair loss.
• Eye : Eye inflammation.
• Genitourinary : Absence of menstrual periods and decrease in sperm count.
Monitor liver function, kidney function, and white blood cell counts regularly while taking this medication.
Store it at 8°C and in the container it came in.
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