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Thioridazine - Indications, Dosage, Side Effects and Precautions

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Information about Thioridazine

Generic Name : Thioridazine
Up-to-date prescription details regarding Thioridazine are provided here.

Pronunciation : thye oh rid' a zeen

Learn the correct pronunciation of the Thioridazine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y49.3 Therapeutic Classification : Psychotherapeutics

Trade Names/Brand Names of Thioridazine

India :

International :


Thioridazine, Mellaril

Why is Thioridazine Prescribed? (Indications)

This medication is a tranquilizer, prescribed for schizophrenia.

When should Thioridazine not be taken? (Contraindications)

Contraindicated in patients with decreased level of consciousness, severe high or low blood pressure, low levels of potassium in the blood, abnormal heart function test (ECG), who are taking antiarrhythmic drugs, antidepressants, and hypersensitivity.

What is the dosage of Thioridazine?

Adult: PO- Schizophrenia- Initial: 50-100; 3 times per day. Max: 800 mg/day in 2-4 divided doses.
Depression- Initial: 25 mg 3 times per day. Maintenance: 20-200 mg/day.

How should Thioridazine be taken?

It comes as a tablet and liquid to take by mouth, with or without food.

What are the warnings and precautions for Thioridazine?

• Caution should be exercised in patients with history of heart problems, high or low blood pressure, blood problems (eg, porphyria), bone marrow depression, liver, kidney problems, enlarged prostate gland, epilepsy, Parkinson’s disease, Reye syndrome, breast cancer, increased eye pressure, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.

• It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• Do not become overheated in hot weather; otherwise it may cause heatstroke.

• Patient may develop with increased risk of neuroleptic malignant syndrome (NMS) and tardive dyskinesia with the following symptoms: body heat, muscle rigidness, altered mental abilities, irregular or fast heartbeat, sweating. If it is so consult with your healthcare provider.

• Avoid long-term use of this medication; otherwise involuntary and uncontrollable movements may develop.

What are the side effects of Thioridazine?

Central Nervous System - Drowsiness, confusion, hyperactivity, tiredness, psychotic reactions, restlessness and headache.
Eye and ENT - Dryness of mouth, blurred vision and nasal stuffiness.
Gastrointestinal - Constipation, nausea, vomiting and diarrhea.
Metabolic - Spontaneous milk secretion, breast engorgement, absence of menstrual periods, inhibition of ejaculation and swelling in the extremities.
Skin - Skin inflammation, skin eruptions and sensitivity to light.

What are the other precautions for Thioridazine?

Avoid excess dosage.

What are the storage conditions for Thioridazine?

Store it at room temperature.
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