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Tetrabenazine - Indications, Dosage, Side Effects and Precautions

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Information about Tetrabenazine

Generic Name : Tetrabenazine
Pronunciation : TET-ra-BEN-a-zine
Latest prescription information about Tetrabenazine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Central Nervous System Agents
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Trade Names/Brand Names of Tetrabenazine

India : 

International : 

Xenazine
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Why is Tetrabenazine Prescribed? (Indications)

This medication is a monoamine depleter, prescribed for involuntary movements (chorea) in patients with Huntington's disease. It works by reducing the amount of certain chemicals in the brain.

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When should Tetrabenazine not be taken? (Contraindications)

Contraindicated in patients with suicidal thoughts, depression, severe liver impairment, who are taking reserpine, and hypersensitivity.

What is the dosage of Tetrabenazine?

PO- The starting dose should be 12.5 mg per day given once in the morning. The maximum recommended single dose is 25 mg. Maximum: 50mg.

How should Tetrabenazine be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Tetrabenazine?

• Caution should be exercised in patients with history of heart diseases, electrolyte problems, breast cancer, CYP2D6 poor metabolizer, depression, suicidal thoughts, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause drowsiness or dizziness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.

Avoid alcohol consumption.

Patient may develop with increased risk of neuroleptic malignant syndrome (NMS) with the following symptoms: fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; or sweating. If it is so consult with your doctor.

What are the side effects of Tetrabenazine?

   Central Nervous System : Weakness, balance difficulty, slow movement, dizziness, speech disorder, unsteadiness, headache, drowsiness, sleeplessness, depression, anxiety, irritability and decreased appetite.
   Gastrointestinal : Nausea, and vomiting.
   Body as a Whole : Fatigue, tear-like wounds, and bruising.
   Respiratory : Upper respiratory tract infection, shortness of breath, and lung inflammation.
   Genitourinary : Painful urination.

What are the other precautions for Tetrabenazine?

Avoid excess dosage.

What are the storage conditions for Tetrabenazine?

Store it at room temperature (25C).




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Comments

ramji_04, India

TETRABENAZINE forwarded under the name REVOCON is now unavailable in the market [Hyderabad] - reasons unknown. This is a very important medicine for many patients like me. Kindly make available in the market at the earliest.

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