This medication is a monoamine depleter, prescribed for involuntary movements (chorea) in patients with Huntington's disease. It works by reducing the amount of certain chemicals in the brain.
Contraindicated in patients with suicidal thoughts, depression, severe liver impairment, who are taking reserpine, and hypersensitivity.
PO- The starting dose should be 12.5 mg per day given once in the morning. The maximum recommended single dose is 25 mg. Maximum: 50mg.
It comes as a tablet to take by mouth, with or without food.
• Caution should be exercised in patients with history of heart diseases, electrolyte problems, breast cancer, CYP2D6 poor metabolizer, depression, suicidal thoughts, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• It may cause drowsiness or dizziness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
• Avoid alcohol consumption.
• Patient may develop with increased risk of neuroleptic malignant syndrome (NMS) with the following symptoms: fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; or sweating. If it is so consult with your doctor.
• Central Nervous System :
Weakness, balance difficulty, slow movement, dizziness, speech disorder, unsteadiness, headache, drowsiness, sleeplessness, depression, anxiety, irritability and decreased appetite.
• Gastrointestinal : Nausea, and vomiting.
• Body as a Whole : Fatigue, tear-like wounds, and bruising.
• Respiratory : Upper respiratory tract infection, shortness of breath, and lung inflammation.
• Genitourinary : Painful urination.
Avoid excess dosage.
Store it at room temperature (25°C).