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Telaprevir - Indications, Dosage, Side Effects and Precautions

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Information about Telaprevir

Generic Name : Telaprevir
Up-to-date prescription details regarding Telaprevir are provided here.

Pronunciation : tel-A-pre-vir

Learn the correct pronunciation of the Telaprevir, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y41.5 Therapeutic Classification : Antivirals

Trade Names/Brand Names of Telaprevir

International :


Incivek

Why is Telaprevir Prescribed? (Indications)

This medication is a hepatitis C virus protease inhibitor, prescribed for chronic hepatitis C virus infection with other medications.  It decreases the amount of hepatitis C virus (HCV) in the body.

When should Telaprevir not be taken? (Contraindications)

Contraindicated in pregnant women, men whose female partners are pregnant, co-administration with drugs that are highly dependent on CYP3A such as alfuzosin, certain benzodiazepines, cabazitaxel, cisapride, conivaptan, dronedarone, ergot derivatives, lurasidone, pimozide, rifabutin, rifampin, rivaroxaban, silodosin, PDE5 inhibitor, St. John's wort, or tolvaptan, and hypersensitivity.

What is the dosage of Telaprevir?

Adult- PO- The recommended dose is 750 mg (two 375-mg tablets) taken orally 3 times a day.

How should Telaprevir be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Telaprevir?

• Caution should be exercised in patients with history of HIV infection, gout, blood problems (anemia, low blood platelet levels, or low white blood cell levels), liver impairment, had an organ transplant, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• It may reduce platelet counts; avoid injury or bruising.

• Avoid contact with people who have infections in order to prevent the spread of infection.

• Monitor complete blood cell counts, electrolyte levels, liver and kidney function, hepatitis C virus antibody levels, thyroid function, and uric acid levels regularly while taking this medication.

Patient may develop Stevens Johnson Syndrome (SJS), Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), and Toxic Epidermal Necrolysis (TEN).

What are the side effects of Telaprevir?

Rash, anemia, fatigue, itching, nausea, and vomiting.

What are the other precautions for Telaprevir?

Avoid excess dosage.

What are the storage conditions for Telaprevir?

Store it at controlled room temperature (25°C).
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