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General Information on Sulphamethoxazole Pyrimethamine

Generic Name : Sulphamethoxazole Pyrimethamine

Pronunciation : sul-fo-meth-sox-a-zole+pyr-I-meth-amine

Latest prescription information about Sulphamethoxazole Pyrimethamine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.2 | Therapeutic Classification : Anti- Malarials

Trade Names/Brand Names of Sulphamethoxazole Pyrimethamine

India- Malarwin.
International- Fansidar.

Why is Sulphamethoxazole Pyrimethamine Prescribed? (Indications)

This medication is an antimalarial agent, prescribed for malaria. 

What is the dosage of Sulphamethoxazole Pyrimethamine?

Adults: Prophylaxis- 1 tab (combination in the ratio of 500mg sulphamethaxarole + 25mg pyrimethamine) once a week. Treatment: 2 tabs in a single dose.
Children: 9-14 years: 3/4 tab 4-8 years: 1/2 tab under 4: 1/4 tab. All once a week.

How should Sulphamethoxazole Pyrimethamine be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Sulphamethoxazole Pyrimethamine?

Caution should be exercised in patients with history of G6PD deficiency, asthma, severe allergies, kidney or liver problems, seizures, alcohol abuse, or depression, diarrhea, sore throat, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
It may reduce platelet counts; avoid injury or bruising.
Avoid exposure to sunlight.

What are the side effects of Sulphamethoxazole Pyrimethamine?

   Blood : Anemia, decrease in platelet and white blood cells and easy bruising.
   Skin : Skin death, hives, itching, rash, redness, scar, sensitivity to light and hair loss.
   Gastrointestinal : Mouth ulcer, nausea, blood vomiting, abdominal pains, liver inflammation, liver damage, diarrhea, feeling of fullness, and transient rise of liver enzymes.
   Central Nervous System : Headache, nerve disease, mental depression, convulsions, incoordination, hallucinations, ringing in the ear, unsteadiness, sleeplessness, fatigue, muscle weakness and nervousness.
   Respiratory : Lung infection/inflammation.
   Genitourinary : Kidney failure, interstitial nephritis, BUN and absence of urination.
   Miscellaneous : Drug fever and chills.

What are the other precautions for Sulphamethoxazole Pyrimethamine?

Avoid excess dosage.

What are the storage conditions for Sulphamethoxazole Pyrimethamine?

Store it at room temperature.

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