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Streptokinase - Indications, Dosage, Side Effects and Precautions

Last Updated on August 11, 2022
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Information about Streptokinase

Generic Name : Streptokinase
Up-to-date prescription details regarding Streptokinase are provided here.
Pronunciation : strep-toe-KYE-nase
Learn the correct pronunciation of the Streptokinase, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
ICD Code : Y43.6 | Therapeutic Classification : Enzymes

Overview of Streptokinase

Note: This brand is not available in US market.

Why is Streptokinase Prescribed? (Indications)

This medication is an enzyme, prescribed for heart attack, pulmonary embolism and deep vein thrombosis. It breaks up and dissolves blood clots that can block arteries.  

When should Streptokinase not be taken? (Contraindications)

Contraindicated in patients with high blood pressure, recent stroke, brain tumor, peptic ulcer, intestinal ulcer, inflammation of pancreas, blood clot defects due to liver or kidney disease, recent surgery, childbirth, trauma, active internal bleeding, during pregnancy and hypersensitivity.

What is the dosage of Streptokinase?

IV- Acute MI- 1.5 million units as a single dose immediately after onset of symptoms.
Pulmonary thromboembolism; Arteriovenous occlusions Loading dose: 250,000 units via infusion. Maintenance: 100,000 u/hour for 24-72 hour depending on the condition treated.

How should Streptokinase be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Streptokinase?

• Caution should be exercised in patients with history of vision problems due to diabetes, bleeding disorders, high blood pressure, infection in heart valves, recent biopsy or surgery, recent injury, any allergy and elderly.

What are the side effects of Streptokinase?

  Most Common: Bleeding.
  Allergic Reactions: Fever, shivering, difficulty in breathing, asthma, rash, hives, itching, flushing, nausea and headache.
  Respiratory: Respiratory depression.

What are the other precautions for Streptokinase?

Avoid excess dosage.

What are the storage conditions for Streptokinase?

Store unopened vials at controlled room temperature (15-30C) and in an airtight container.
Last Updated : August 11, 2022

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MAITY45, India

my wife was choosen to inject this medicine while she had acute cheast pain thinking that she had a massive arterial attack. she is diabatic for last 25 years having good control of blood sugar by onglyza 5 mg tab associated with met form ajulux 2 mf. she is ok now but really she did suffer with heart attack as DR.THOUGHT. SO I AM ENQUIRING ABOUT SIDE EFFECT.NO BLEEDING ETC.

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