Note: This brand is not available in US market.
This medication is an enzyme, prescribed for heart attack, pulmonary embolism and deep vein thrombosis. It breaks up and dissolves blood clots that can block arteries.
Contraindicated in patients with high blood pressure, recent stroke, brain tumor, peptic ulcer, intestinal ulcer, inflammation of pancreas, blood clot defects due to liver or kidney disease, recent surgery, childbirth, trauma, active internal bleeding, during pregnancy and hypersensitivity.
IV- Acute MI- 1.5 million units as a single dose immediately after onset of symptoms.
Pulmonary thromboembolism; Arteriovenous occlusions Loading dose: 250,000 units via infusion. Maintenance: 100,000 u/hour for 24-72 hour depending on the condition treated.
It comes as a solution for injection to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of vision problems due to diabetes, bleeding disorders, high blood pressure, infection in heart valves, recent biopsy or surgery, recent injury, any allergy and elderly.
• Most Common:
• Allergic Reactions: Fever, shivering, difficulty in breathing, asthma, rash, hives, itching, flushing, nausea and headache.
• Respiratory: Respiratory depression.
Avoid excess dosage.
Store unopened vials at controlled room temperature (15-30°C) and in an airtight container.
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