Written & Compiled by Anushta Chandrapalan, M.Sc Biotechnology | Medically Reviewed by The Medindia Medical Review Team
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General Information on Sodium Polystyrene Sulfonate

Generic Name : Sodium Polystyrene Sulfonate

Pronunciation : SOE-dee-um POL-ee-STYE-reen SUL-foe-nate

Latest prescription information about Sodium Polystyrene Sulfonate. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Potassium-removing Resin

Trade Names/Brand Names of Sodium Polystyrene Sulfonate

International- Kayexalate, Kionex, SPS.

Other Name(s) of Sodium Polystyrene Sulfonate


Potassium removal Polysterene Sulphonate Resin.

Why is Sodium Polystyrene Sulfonate Prescribed? (Indications)

This medication is a potassium-removing resin, prescribed for hyperkalemia (without ECG changes).  It affects the exchange of sodium and potassium in the body.

When should Sodium Polystyrene Sulfonate not to be taken? (Contraindications)

Contraindicated in patients with obstructive bowel disease, and hypersensitivity.

What is the dosage of Sodium Polystyrene Sulfonate?

Dosage: Adults: PO- The recommended dose is 15 g, 3-4 times daily in water. Children: 0.5- 1 g/kg daily in divided doses.

How should Sodium Polystyrene Sulfonate be taken?

It comes as a powder to take by mouth, with water.

What are the warnings and precautions for Sodium Polystyrene Sulfonate?

Caution should be exercised in patients with history of heart or kidney disease, high blood pressure, constipation, any allergy, who are taking other medications, during pregnancy and breastfeeding.

Monitor blood potassium and other blood electrolyte levels, and electrocardiograms (ECGs) regularly while taking this medication.

What are the side effects of Sodium Polystyrene Sulfonate?

   Gastrointestinal : Rectal ulceration, GI irritation, anorexia, nausea, vomiting, constipation and diarrhea.

What are the other precautions for Sodium Polystyrene Sulfonate?

Avoid excess dosage.

What are the storage conditions for Sodium Polystyrene Sulfonate?

Store in a dry place below 30C.
Suspensions of the resin should be freshly prepared and not to be stored beyond 24 hours.

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