Information about Sodium Nitroprusside

Generic Name : Sodium Nitroprusside
Up-to-date prescription details regarding Sodium Nitroprusside are provided here.

Pronunciation : nye-troe-PRUSS-ide SO-dee-uhm

Learn the correct pronunciation of the Sodium Nitroprusside, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y52.5 Therapeutic Classification : Anti- Hypertensives

Trade Names/Brand Names of Sodium Nitroprusside

India :

Niside | Sonide | Nipress

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International :

Nitropress, Nipride

Why is Sodium Nitroprusside Prescribed? (Indications)

This medication is a potent vasodilator, prescribed for controlling low blood pressure in order to reduce bleeding during surgery. It is also used for high blood pressure.

When should Sodium Nitroprusside not be taken? (Contraindications)

Contraindicated in patients with compensatory hypertension, patients with known inadequate cerebral circulation, congenital (Leber's) optic atrophy or with tobacco amblyopia, congestive heart failure, and hypersensitivity.

What is the dosage of Sodium Nitroprusside?

Adult: IV- Hypertensive crisis- For patients not receiving any antihypertensives: Initial: 0.3-1.5 mcg/kg/min, adjust gradually if needed.
Induction of hypotension during anesthesia- Recommended maximum dose is 1.5 mcg/kg/min.

How should Sodium Nitroprusside be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Sodium Nitroprusside?

• Caution should be exercised in patients with under active thyroid, kidney or liver impairment, heart disease, stroke, elderly, lung disease, anemia, dehydration, absence of urination, during pregnancy and breastfeeding.

• Monitor acid-based metabolic problems and avoid excess dosage in order to minimize cyanide accumulation.

• Avoid abrupt withdrawal.

What are the side effects of Sodium Nitroprusside?

Serious Effects - Thiocyanate toxicity, cyanide toxicity and increased intracranial pressure.
Most Common - Abdominal pain, apprehension, diaphoresis, dizziness, headache, muscle twitching, nausea, palpitations, restlessness and retching.
Heart - Slow or fast heart rate and electrocardiographic changes.
Skin - Rash.
Metabolic - Underactive thyroid.
Gastrointestinal - Ileus.
Blood - Decreased platelet aggregation.
Central Nervous System - Stroke.
Miscellaneous - Flushing, venous streaking, irritation at the infusion site.