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Simvastatin and Sitagliptin - Indications, Dosage, Side Effects and Precautions

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Information about Simvastatin and Sitagliptin

Generic Name : Simvastatin and Sitagliptin
Up-to-date prescription details regarding Simvastatin and Sitagliptin are provided here.

Pronunciation : SIM va stat in and SIT a GLIP tin

Learn the correct pronunciation of the Simvastatin and Sitagliptin, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Trade Names/Brand Names of Simvastatin and Sitagliptin

International :


Juvisync

Why is Simvastatin and Sitagliptin Prescribed? (Indications)

This combination medication contains antidiabetic and cholesterol-lowering agent, prescribed for treating type 2 diabetes and lowering high cholesterol. It works by reducing bad cholesterol level and by regulating the levels of insulin.

When should Simvastatin and Sitagliptin not be taken? (Contraindications)

Contraindicated in patients with type 1 diabetes, diabetic ketoacidosis, severe kidney problem, and pregnant and breastfeeding women.
It should not be co-administered with CYP3A4 inhibitors.

What is the dosage of Simvastatin and Sitagliptin?

The recommended starting dose is 100-mg/40 mg per day.

How should Simvastatin and Sitagliptin be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Simvastatin and Sitagliptin?

• Caution should be exercised in patients with history of low blood pressure, kidney problems, low thyroid function, muscle problems or a family history of muscle problems, or serious metabolic, hormonal, or electrolyte problems, seizures, liver problems, or alcohol abuse, angioedema, any allergy, who are taking other medications, elderly, children.

• Follow the diet and exercise program as directed by your physician.

What are the side effects of Simvastatin and Sitagliptin?

Body as a Whole - Swelling, abdominal pain.
Heart - Abnormal heart rhythm.
Gastrointestinal - Constipation, stomach inflammation.
Metabolic - Diabetes mellitus.
Musculoskeletal - Muscle pain and Immune-mediated necrotizing myopathy (IMNM).
Central Nervous System - Headache, sleeplessness, fainting.
Respiratory - Lung inflammation.
Skin - Eczema.
Genitourinary - Urinary tract infection.

What are the other precautions for Simvastatin and Sitagliptin?

Avoid excess dosage.

What are the storage conditions for Simvastatin and Sitagliptin?

Store at 20-25°C.
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