This medication is an anticholinergic agent, prescribed for prevention of symptoms of motion sickness such as nausea and vomiting, and recovery from anesthesia and surgery.
It is also used to treat certain types of muscle spasm problems (eg. Parkinsonism) and certain stomach or intestinal problems (eg, irritable bowel syndrome).
It may be used as eye drops in cases of eye inflammation.
Contraindicated in patients allergic to the drug, those with narrow angle glaucoma.
PO- Genito-urinary spasm; Gastrointestinal tract spasm As butyl bromide: 20 mg 4 times/day.
To prevent nausea and vomiting: IV/IM/SC- As hydro bromide: 300 mcg 30 minutes before journey, then 300 mcg 6 hourly if needed. Max: 3 doses in 24 hours.
Prevention of motion sickness: 1.5 mg patch should be applied behind the ear at least 4 hours before journey.
It comes as a tablet to take by mouth, with or without food.
It is also available as an injection, eye drops and a patch to be applied on the skin behind the ear.
• Caution should be exercised in patients with history of liver or kidney disease, pyloric stenosis(obstruction at lower end of stomach), urinary retention, prostatic hyperplasia, psychosis, seizure disorders, ulcerative colitis, coronary artery disease, fast heart rhythm, heart failure, high blood pressure , elderly, children, during pregnancy and breastfeeding.
• Limit alcohol intake while taking this medication.
• You should wash your hands thoroughly with soap and water immediately after using this medication.
• Most common:
Dryness of mouth, difficulty in swallowing, talking, dizziness.
• Central Nervous system: Confusion, headache, restlessness, hallucinations, memory disturbances.
• Eye: Blurring of vision, increased sensitivity to light, increased eye pressure in patients suffering from narrow angle glaucoma.
• Skin: Flushing, irritation, and rashes.
• Genitourinary: Retention of urine.
• Heart: Variations in blood pressure.
• Potentially Fatal: Central Nervous System depression, coma, circulatory and respiratory failure.
If there is no improvement in your health condition, consult with your doctor.
Ophthalmic: Store at 8-27°C.
Oral: Store at room temperature of 15-30°C.
Parenteral: Store at room temperature of 15-30°C (58-86°F).
Subcutaneous: Store at room temperature of 15-30°C.
Transdermal: Store at 20-25°C .Store at room temperature.
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