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Saquinavir - Indications, Dosage, Side Effects and Precautions

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Information about Saquinavir

Generic Name : Saquinavir
Up-to-date prescription details regarding Saquinavir are provided here.

Pronunciation : sa-KWIN-a-veer

Learn the correct pronunciation of the Saquinavir, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y41.5 Therapeutic Classification : Antiretroviral Agents

Trade Names/Brand Names of Saquinavir

India :

International :


Invirase , Fortovase.

Why is Saquinavir Prescribed? (Indications)

This medication is a protease inhibitor, prescribed for human immunodeficiency virus (HIV) infection in patients with or without acquired immunodeficiency syndrome (AIDS) with other medication. It slows the spread of HIV in the body.

When should Saquinavir not be taken? (Contraindications)

Contraindicated in patients with severe liver damage, in breastfeeding women, and hypersensitivity.

What is the dosage of Saquinavir?

PO- HIV infection Combined with other antiretroviral: In patients more than 16 years: 1 g twice daily with ritonavir. Take antiretroviral medications (ARVs) as soon as possible after exposure to HIV 1g twice daily with ritonavir and other antiretroviral and continue for 4 weeks if tolerated.

How should Saquinavir be taken?

It comes as a tablet and capsule. It is taken twice a day on a full stomach but can be delayed up to 2 hours after a meal. A soft gelatin capsule is also available that has to be taken 3 times a day.

What are the warnings and precautions for Saquinavir?

•Caution needed for pregnant women, adolescents <16 years, elderly, patients with history of liver or kidney damage, diabetes, group of genetic disorders.

It may increase triglyceride and lipid levels.

It may affect your blood sugar. Check blood sugar regularly.

• It does not stop the spread of HIV to others; avoid sexual contact, sharing of needles, or injection supplies
.

What are the side effects of Saquinavir?

Gastrointestinal- Nausea, vomiting, diarrhea, taste disturbance, abdominal pain, loss of appetite, increased appetite, excessive stomach gas.
Central Nervous System-Fatigue, sleep disturbances, headache, dizziness.
Skin- Itching, and exacerbation of diabetes, in growing toenails and nail infection of the great toes, hypersensitivity.
Blood- Blood disorders, Irregular, prolonged heavy menstruation.
Miscellaneous- Sexual dysfunction.

What are the other precautions for Saquinavir?

It may cause dizziness or vision problem. Do not drive a car, operate machinery, or do anything else that could be dangerous.

What are the storage conditions for Saquinavir?

Store at 25°C. Keep in an airtight container. Keep away from children.
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