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Ruxolitinib - Indications, Dosage, Side Effects and Precautions

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Information about Ruxolitinib

Generic Name : Ruxolitinib
Up-to-date prescription details regarding Ruxolitinib are provided here.

Understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Trade Names/Brand Names of Ruxolitinib

International :


Jakafi

Why is Ruxolitinib Prescribed? (Indications)

This medication is a kinase inhibitor, prescribed for high-risk myelofibrosis. It blocks certain substances (JAK1 and JAK2) that are involved in myelofibrosis.

When should Ruxolitinib not be taken? (Contraindications)

Contraindicated in patients with known hypersensitivity.

What is the dosage of Ruxolitinib?

PO- The starting dose is 20 mg 2 times per day, for patients with platelet count greater than 200 X 109/L.

How should Ruxolitinib be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Ruxolitinib?

• Caution should be exercised in patients with history of liver or kidney impairment, patients on dialysis, during pregnancy and breastfeeding.

• It may cause dizziness, avoid performing any hazardous activity while taking this medication.

• Patient may develop with certain types of infection; discuss with your healthcare provider before taking this medication.

• It may reduce platelet counts; avoid injury or bruising.

• Monitor complete blood count regularly while taking this medication.

What are the side effects of Ruxolitinib?

Most Frequent - Thrombocytopenia and anemia.
Miscellaneous - Bruising, dizziness, headache, urinary tract infection, weight gain, flatulence, herpes zoster.

What are the other precautions for Ruxolitinib?

Avoid excess dosage.

What are the storage conditions for Ruxolitinib?

Store it at room temperature (20° to 25°C).
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