Information about Romidepsin

Generic Name : Romidepsin
Up-to-date prescription details regarding Romidepsin are provided here.

Pronunciation : ROE-mi-DEP-sin

Learn the correct pronunciation of the Romidepsin, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Trade Names/Brand Names of Romidepsin

International :

Istodax

Why is Romidepsin Prescribed? (Indications)

This medication is a histone deacetylase (HDAC) inhibitor, prescribed for cutaneous T-cell lymphoma (CTCL) or peripheral T-cell lymphoma (PTCL). It works by slowing the growth of cancer cells.

When should Romidepsin not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Romidepsin?

IV- The recommended dose is 14 mg/m², over a 4-hour period infusion on days 1, 8 and 15 of a 28-day cycle.

How should Romidepsin be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Romidepsin?

• Caution should be exercised in patients with history of liver or kidney impairment, irregular heartbeat or other heart diseases, nausea, vomiting, or diarrhea, who have undergone chemotherapy, any allergy, during pregnancy and breastfeeding.

• It may reduce platelet counts; avoid injury or bruising.

• Patient may develop with increased risk of tumor lysis syndrome (TLS) with the following symptoms: irregular heartbeat, fainting, decreased urination, muscle weakness or cramps, nausea, vomiting, diarrhea, or loss of appetite. If it is so consult with your doctor.

• Monitor complete blood cell counts, blood electrolyte levels, and electrocardiograms (ECGs) regularly while taking this medication.

What are the side effects of Romidepsin?

Gastrointestinal - Nausea, vomiting, diarrhea, constipation, abdominal pain, mouth ulcer, indigestion, loss of appetite.
Central Nervous System - Weakness, fatigue, headache.
Metabolic - Decreased weight and fluid retention.
Blood - Anemia, decrease in white blood cells and platelets.
Miscellaneous - Fever, chills, cough, difficulty in breathing, fast heart rate.