Ritonavir - Indications, Dosage, Side Effects and Precautions


Information about Ritonavir

Generic Name : Ritonavir
Up-to-date prescription details regarding Ritonavir are provided here.

Pronunciation : ri toe' na veer

Learn the correct pronunciation of the Ritonavir, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y41.5 Therapeutic Classification : Antiretroviral Agents

Trade Names/Brand Names of Ritonavir

India :

International :

Norvir, Norvir Soft Gelatin

Why is Ritonavir Prescribed? (Indications)

This medication is an antiretroviral agent, prescribed for HIV (Human Immunodeficiency Virus) infection either alone or combined with other antiretroviral agents. It is a protease inhibitor.

When should Ritonavir not be taken? (Contraindications)

Hypersensitivity, co-administering with other protease inhibitors and interaction with other medications may cause life-threatening reactions.

What is the dosage of Ritonavir?

Adult: PO- HIV infection: The recommended dose is 600mg, two times per day.

How should Ritonavir be taken?

It comes as a tablet, capsule and solution to take by mouth; it should be taken with food.

What are the warnings and precautions for Ritonavir?

• If you are taking any medication, inform your doctor.

• Caution should be exercised in patients with history of prolonged QT interval (irregular heart beats), heart, liver or kidney disease, diabetes, bleeding disorder, high cholesterol, elderly, pregnant and breastfeeding.

• It may reduce the effectiveness of contraceptives.

• In some patient’s cholesterol, sugar level may be increased with the following symptoms: increased thirst, increased urination, confusion, drowsiness, flushing, and rapid breathing; if it so, inform your doctor.

• Monitor glucose, lipid, uric acid and blood counts.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Ritonavir?

Body as a Whole- Abdominal Pain, weakness, fever, dry mouth, jaundice and uneasiness.
Heart- Fainting, dilatation of blood vessels, high/low blood pressure, heart attack, palpitation, postural hypotension and fast heart rate.
Gastrointestinal- Loss of appetite, constipation, nausea, vomiting, diarrhea, indigestion, fecal incontinence, flatulence, abnormal stools, bloody diarrhea, inflammation of colon, dry mouth, difficulty in swallowing, esophageal ulcer and gastrointestinal disorder.
Local - Throat irritation.
Metabolic - Weight loss and an increased sugar level.
Musculoskeletal - Joint/Muscle pain.
Central Nervous System - Headache, anxiety, tingling, numbness, confusion, depression, dizziness, sleeplessness, drowsiness and abnormal thinking.
Respiratory- Inflammation of pharynx, asthma, difficulty in breathing, nosebleed, hiccup and respiratory depression.
Skin - Rash and sweating
Eye and ENT- Taste perversion, abnormal vision, blurred vision, inflammation of eyelid/ conjunctiva, ear pain, eye disorder, hearing impairment, increased earwax, distorted sense of smell, and photophobia (light sensitivity).
Genitourinary- Urination at night time, acute kidney failure, absence of urination, blood in urine, impotence, kidney stone, heavy bleeding during menstrual period, penis disorder, increased urinary frequency, urinary tract infection and inflammation of vagina.

What are the other precautions for Ritonavir?

Avoid alcoholic beverages.
Drink adequate water or liquid, to avoid dehydration.

What are the storage conditions for Ritonavir?

Tablet and capsule: Store it in refrigerator, do not freeze it. Keep away from children and pets.