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General Information on Rifampin- Isoniazid- Pyrazinamide

Generic Name : Rifampin- Isoniazid- Pyrazinamide

Latest prescription information about Rifampin- Isoniazid- Pyrazinamide. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Rifampin- Isoniazid- Pyrazinamide

International- Rifater.

Why is Rifampin- Isoniazid- Pyrazinamide Prescribed? (Indications)

This combination medication contains antituberculosis agents, prescribed for pulmonary tuberculosis. 

When should Rifampin- Isoniazid- Pyrazinamide not to be taken? (Contraindications)

Contraindicated in patients with a history of known hypersensitivity.

What is the dosage of Rifampin- Isoniazid- Pyrazinamide?

Patients weighing ≤ 44 kg 4 tablets.
Patients weighing between 45-54 kg 5 tablets.
Patients weighing ≥ 55 kg 6 tablets.

How should Rifampin- Isoniazid- Pyrazinamide be taken?

It comes as a tablet to take by mouth, 1 hour before or 2 hours after a meal with a full glass of water.

What are the warnings and precautions for Rifampin- Isoniazid- Pyrazinamide?

Caution should be exercised in patients with history of diabetes, epilepsy, gout, HIV infection, alcoholism, liver or kidney impairment, malnutrition, elderly, children, any allergy, during pregnancy and breastfeeding.

What are the side effects of Rifampin- Isoniazid- Pyrazinamide?

   Gastrointestinal : Heartburn, epigastric distress, loss of appetite, nausea, vomiting, jaundice, flatulence, cramps, and diarrhea.
   Liver : Abnormalities in liver function tests.
   Blood : Anemia and decrease in white blood cells.
   Central Nervous System : Headache, fever, drowsiness, fatigue, incoordination, dizziness, inability to concentrate, mental confusion, behavioral changes, muscle weakness, pains in extremities.
   Eye : Visual disturbances.
   Endocrine : Menstrual disturbances.
   Genitourinary : BUN.
   Hypersensitivity : Itching, rash, erythema multiforme including Stevens-Johnson Syndrome, toxic epidermal necrolysis, sore mouth, sore tongue and eye inflammation.
   Miscellaneous : Fever, chills, bone pain, shortness of breath, wheezing, decrease in blood pressure and shock.

What are the other precautions for Rifampin- Isoniazid- Pyrazinamide?

Avoid excess dosage

What are the storage conditions for Rifampin- Isoniazid- Pyrazinamide?

Store at a room temperature between 15C to 30C
Protect from excess humidity

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