Information about Ramipril
Generic Name : Ramipril
Pronunciation : ra mi' pril
Latest prescription information about Ramipril. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y52.4
Therapeutic Classification : ACE Inhibitors
Trade Names/Brand Names of Ramipril
Why is Ramipril Prescribed? (Indications)
This medication is an angiotensin-converting enzyme (ACE) inhibitor, used alone or in combination with other medications to treat high blood pressure. It is also used to reduce the risk of heart attack and stroke in patients at risk for these problems and to improve survival in patients with heart failure after a heart attack.
When should Ramipril not be taken? (Contraindications)
Contraindicated in patients with hypersensitivity, bilateral renal artery stenosis (narrowing of the arteries going to the kidney), or a single kidney with unilateral renal artery stenosis, aortic stenosis or outflow tract obstruction, pregnancy and breastfeeding.
What is the dosage of Ramipril?
PO- Hypertension- Initial: 1.25 mg at bedtime. Maintenance: 2.5-5 mg/day as a single dose, up to 10 mg/day if needed.
Heart failure- Initial: 1.25 mg once daily. Max: 10 mg/day.
Myocardial infarction (Heart Attack)- Start 3-10 days after infarction. Initial: 2.5 mg twice daily after 2 days, then 5 mg twice daily. Maintenance: 2.5-5 mg twice daily.
How should Ramipril be taken?
It comes as a capsule to take by mouth. It is usually taken once or twice a day with or without food.
What are the warnings and precautions for Ramipril?
• It may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. Get up slowly from bed.
• It may cause a serious side effect called angioedema with symptoms of swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness.
• It may affect your blood sugar. Check blood sugar levels closely.
• Monitor kidney function before and during treatment.
• Regular monitoring of white blood cells in patients with vascular collagen disorders is recommended.
• Use with caution in patients with history of an allergic reaction which included swelling of the face/lips/tongue/throat (angioedema). Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, high blood levels of potassium, heart problems, severe dehydration (and loss of electrolytes such as sodium), diabetes (poorly controlled), strokes, blood vessel disease (e.g., collagen vascular diseases such as lupus, scleroderma) and children.
What are the side effects of Ramipril?
• Heart: Low blood pressure, chest pain, loss of consciousness.
• Central Nervous System: Dizziness.
• Gastrointestinal: Nausea, vomiting, diarrhea.
• Genitourinary: Abnormal kidney function.
• Blood: Severe decrease in white blood cells.
• Metabolic: Increase in potassium in blood.
• Respiratory: Cough.
• Miscellaneous: Severe allergic reactions.
What are the other precautions for Ramipril?
Dehydration, excessive sweating, vomiting, or diarrhea may increase the risk of low blood pressure. So monitor blood pressure regularly.
What are the storage conditions for Ramipril?
Store at 25 ï¿½C. Store it in an airtight container and keep away from children.