Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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General Information on Propofol

Generic Name : Propofol

Pronunciation : PROE-poe-fol

Latest prescription information about Propofol. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y48.2 | Therapeutic Classification : General Anesthetics

Why is Propofol Prescribed? (Indications)

This medication is a general anesthetic, prescribed for induction and maintenance of general anaesthesia. 

When should Propofol not to be taken? (Contraindications)

Contraindicated in patients with allergies to eggs, egg products, soybeans or soy products, and hypersensitivity.

What is the dosage of Propofol?

Adult- Induction: 40 mg by inj or infusion every 10 sec. Usual dose: 1.5-2.5 mg/kg. Maintenance: 4-12 mg/kg/hour or intermittent bolus inj of 20-50 mg.
Child- >8 year: Induction dose of 2.5 mg/kg. Maintenance dose: 9-15 mg/kg/hour by IV infusion or intermittent bolus inj.
Elderly- Including neurosurgical and debilitated patients: Infuse at a rate of 20 mg every 10 sec. Maintenance: 3-6 mg/kg/hour. Usual dose needed: 1-1.5 mg/kg.

How should Propofol be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Propofol?

It may decrease mental alertness for some time after use. This effect may be worse if you drink alcohol or take certain medicines.

Do not use it in newborns or infants. It may cause serious and sometimes fatal nervous system problems and other side effects.

It should not be used to start anesthesia in children younger than 3 years old.

What are the side effects of Propofol?

  Central Nervous System: Involuntary muscle movements.
  Gastrointestinal: Nausea, vomiting.
  Miscellaneous: Headache, fever; pain, burning or stinging at injection site.

What are the other precautions for Propofol?

Monitor the signs of low blood pressure regularly.

What are the storage conditions for Propofol?

It is normally handled and stored by healthcare providers.

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