This medication is a human monoclonal antibody (kinase inhibitor), prescribed for chronic myeloid leukemia (CML).
PO- The recommended dose is 45mg once daily.
It comes a tablet to take by mouth, with or without food.
• Caution should be exercised in patients with history of blood clots, heart, liver or kidney problems, pancreatitis, high blood pressure, bleeding problems, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• Monitor complete blood count, patients for fluid retention, heart rhythm, blood pressure, signs and symptoms of heart failure regularly while taking this medication.
• Ensure adequate hydration otherwise it may lead to dehydration.
• Most Common :
High blood pressure, rash, abdominal pain, fatigue, headache, dry skin, constipation, joint pain, nausea and fever.
• Blood : Anemia, decrease in white blood cells and platelets.
• Miscellaneous : Myelosuppression, abnormal heart rhythm and fluid retention.
• Heart : Heart Failure.
• Gastrointestinal : Constipation, nausea, diarrhea, vomiting, mouth ulcer, GI hemorrhage.
• Infection : Pneumonia, urinary tract infection, upper respiratory tract infection.
• Central Nervous system : Peripheral neuropathy, dizziness.
• Respiratory : Pleural effusion, cough, difficulty in breathing.
• Skin : Rash, dry skin.
• Musculoskeletal : Joint and muscle pain, pain in extremity, back pain, muscle spasms, bone pain.
• General : Weakness.
Avoid excess dosage.
Store it in controlled room temperature (20° to 25°C).
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