This medication is an anti-angiogenic and immunomodulator, prescribed for multiple myeloma.
Contraindicated to pregnant women.
4 mg per day taken orally on days 1-21 of repeated 28-day cycles until disease progression.
It comes as a capsule to take by mouth, without food, at least two hours before or two hours after a meal.
Caution should be exercised in patients with history of smoking, any other medical condition, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Monitor complete blood counts regularly while taking this medication.
Most Common :
Fatigue, weakness, decrease in white blood cells, anemia, constipation, nausea, diarrhea, difficulty in breathing, upper-respiratory tract infections, back pain and fever.
Gastrointestinal : Vomiting.
Infections : Pneumonia, urinary tract infection.
Musculoskeletal : Musculoskeletal pain, chest pain, muscle spasms, joint pain, pain in extremity, muscular weakness, bone pain.
Respiratory : Difficulty in breathing, cough, nosebleed.
Metabolic : Decreased appetite, increase in blood minerals.
Skin : Excess sweat, rash, night sweats, dry skin, itching.
Central Nervous System : Dizziness, tremor, headache, neuropathy peripheral, sleeplessness, confusion, anxiety.
Lab Tests : Blood creatinine increased, weight increased or decreased.
Genitourinary : Kidney failure.
Avoid excess dosage.
Store it at room temperature (20°C to 25°C)
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