Vijayaganesh Kasinathan
Written & Compiled by Pharmacist Vijayaganesh Kasinathan, B.Pharm, M.Pharm
Last Updated on Nov 04, 2017
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Last Updated : 11/4/2017

General Information on Policosanol

Generic Name : Policosanol

Latest prescription information about Policosanol. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Antilipemics

Trade Names/Brand Names of Policosanol

Overview of Policosanol

Policosanol is a dietary supplement that may help in cholesterol reduction.
It is a natural product obtained from plant sources such as sugarcane and beeswax.

Why is Policosanol Prescribed? (Indications)

Policosanol is prescribed to decrease the amount of cholesterol in the blood by reducing the cholesterol synthesis in the liver and increasing the breakdown of bad or LDL cholesterol.

It is also recommended for improving blood circulation by reducing the platelet adherence or stickiness in patients with atherosclerosis, stroke (narrowing of blood vessels causing reduced blood flow or oxygen supply) or intermittent claudication (pain in the legs due to the obstruction of arteries).

 

When should Policosanol not to be taken? (Contraindications)

Policosanol should not be used in patients who are:

Allergy to the policosanol drug
Pregnant or plan to become pregnant
Breastfeeding

What is the dosage of Policosanol?

The recommended initial adult dose of policosanol is 5 to 10 mg once daily taken with the evening meal since the hepatic synthesis of cholesterol is expected to occur at night.
The maximum dosage is 20 mg daily usually taken as 10mg in two divided doses.
The usual adult dose in treating intermittent claudication is 10mg two times daily with food.

How should Policosanol be taken?

Policosanol comes as a capsule or tablet which should be taken by mouth.
It must be swallowed whole with a sufficient quantity of a glass of water preferably taken before bedtime.

What are the warnings and precautions for Policosanol?

Dietary changes and regular exercise are needed along with the policosanol adjunctive therapy.

What are the side effects of Policosanol?

  Gastrointestinal: Diarrhea, nausea, constipation, stomach pain, heartburn, increased appetite
  Cardiovascular system: Abnormalities in blood pressure level
  Central Nervous System: Headache, somnolence, dizziness, sleeplessness, nervousness
  Skin: Rashes, skin irritation and pruritus
  Others: Weight loss, joint pain, increased urination, bleeding from the nose and gums, raised level of liver enzymes

What are the other precautions for Policosanol?

Policosanol should not be used as a first-line treatment for treating hypercholesterolemia but may be regarded as a second line agent in patients who cannot take HMG Co-A reductase inhibitors or other lipid-lowering medications.

What are the Drug Interactions of Policosanol?

Policosanol should not be taken together with blood thinning agents such as aspirin or dipyridamole due to the increased action of anticoagulant or antiplatelet properties.

What are the storage conditions for Policosanol?

Store at a room temperature below 25C away from excess moisture and light.
Keep out of reach of children.

Last Updated : 11/4/2017

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