This combination medication is an antibacterial agent, prescribed for various infections such as Nosocomial pneumonia. It blocks the bacteria's cell wall growth, which kills the bacteria. Tazobactam inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin. It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.
IV- The recommended dose is 3.375 mg 4 times a day, for 7 to 10 days. A higher initial dose of 4.5 mg 4 times a day may be used for more severe infections.
It comes as a solution for injection, administered by a healthcare provider.
• Caution should be exercised in patients with history of asthma; hay fever; or kidney, liver, or gastrointestinal disease (especially colitis), during pregnancy and breastfeeding.
• Repeated electrolyte estimations may be needed especially in patients with low potassium levels.
• Monitor blood functions regularly.
Continue to use this medication until the full prescribed amount is finished.
Injection vials should be stored at (20-25°C) room temperature prior to reconstitution.
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