Information about Piperacillin/Tazobactam

Generic Name : Piperacillin/Tazobactam
Up-to-date prescription details regarding Piperacillin/Tazobactam are provided here.

Pronunciation : PI-per-a-SIL-in/TAZ-oh-BAK-tam

Learn the correct pronunciation of the Piperacillin/Tazobactam, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y40.0 Therapeutic Classification : Antibiotics

Trade Names/Brand Names of Piperacillin/Tazobactam

India :

More info >>>

International :

Zosyn

Why is Piperacillin/Tazobactam Prescribed? (Indications)

This combination medication is an antibacterial agent, prescribed for various infections such as Nosocomial pneumonia. It blocks the bacteria's cell wall growth, which kills the bacteria. Tazobactam inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin. It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.

When should Piperacillin/Tazobactam not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Piperacillin/Tazobactam?

IV- The recommended dose is 3.375 mg 4 times a day, for 7 to 10 days. A higher initial dose of 4.5 mg 4 times a day may be used for more severe infections.

How should Piperacillin/Tazobactam be taken?

It comes as a solution for injection, administered by a healthcare provider.

What are the warnings and precautions for Piperacillin/Tazobactam?

•Caution should be exercised in patients with history of asthma; hay fever; or kidney, liver, or gastrointestinal disease (especially colitis), during pregnancy and breastfeeding.

Repeated electrolyte estimations may be needed especially in patients with low potassium levels.

Monitor blood functions regularly.

What are the side effects of Piperacillin/Tazobactam?

It may lead to increase risk of fever, rashes in patients with cystic fibrosis, bleeding, super infections, convulsions, kidney failure.
Allergic Reactions- Diarrhea, severe allergic reactions, skin rashes, itching, occasionally platelet mediated bleeding, rigors, malaise, inflammation in stomach.
Local- Injection-site reactions such as pain, swelling, redness, indurations and vein inflammation.
Gastrointestinal- Inflammation of stomach, hairy tongue, inflammation of colon, nausea and vomiting, blood in stool.
Genitourinary- Urine retention, painful urination.
Blood- Decrease in white blood cells.
Lab- Increase in liver enzymes, blood urea nitrogen, and presence of red blood cells in urine.
Miscellaneous- Chills, facial swelling, mucosal bleeding, tightness in throat.