Dhanalakshmi Chinnuswamy
Medically Reviewed by The Medindia Medical Review Team on Jul 31, 2012
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General Information on Pentostatin

Generic Name : Pentostatin

Pronunciation : PEN-toe-STAT-in

Latest prescription information about Pentostatin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Pentostatin

International- Nipent.

Why is Pentostatin Prescribed? (Indications)

This medication is an antineoplastic agent, prescribed for certain types of cancer. It prevents the growth of cancer cells.

When should Pentostatin not to be taken? (Contraindications)


What is the dosage of Pentostatin?

IV- For patients with a CrCl at least 60mL/min- The recommended dose is 4 mg/m 2 every other week.

How should Pentostatin be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Pentostatin?

Caution should be exercised in patients with history of infection, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may reduce the platelet counts; avoid bruising or injury.

Avoid contact with people who have infections that may spread to others.

Monitor liver, kidney function, and complete blood cell count while taking this medication.

What are the side effects of Pentostatin?

   Heart : Bleeding, low blood pressure, chest pain, abnormal heart rhythm, fast or slow heart rate, heart arrest, heart failure, high blood pressure, vein inflammation, blood clot, sinus arrest.
   Central Nervous System : Fatigue, headache, neurologic disorder, weakness, anxiety, confusion, depression, dizziness, sleeplessness, nervousness, tingling, drowsiness, abnormal thinking, incoordination, convulsions, speech disorder, emotional lability, hallucination, hostility, inflammation of a nerve, paralysis, syncope, twitching.
   Skin : Rash, itching, sweating, skin disorder, dry skin, hives, pimples, hair loss, photosensitivity.
   ENT : Abnormal vision, deafness, dry eyes, ear pain, tear disorder, photophobia, ringing in the ear, watery eyes.
   Gastrointestinal : Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, mouth infection, dental abnormalities, indigestion, flatulence, gum inflammation, constipation, difficulty in swallowing, tongue inflammation, ileus, unusual taste.
   Genitourinary : Abnormal kidney function, absence of a menstrual period, breast lump, decreased libido, gout, impotence, kidney failure, kidney stone.
   Blood-Lymphatic : Decrease in white blood cells and platelets, anemia.
   Liver : Liver disorder, elevated LFTs.
   Hypersensitivity : Allergic reaction.
   Musculoskeletal : Muscle pain, joint pain, joint inflammation.
   Respiratory : Coughing or increased cough, upper respiratory tract infection, difficulty in breathing, nose inflammation, asthma.
   Miscellaneous : Fever, chills, pain, viral infection, chest pain, death, face swelling, swelling in the extremities, flu-like symptoms and hangover effect.

What are the other precautions for Pentostatin?

Avoid excess dosage.

What are the storage conditions for Pentostatin?

Store the medication as directed by your physician.

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