This medication is 5-HT3 receptor blocker, prescribed for prevention of chemotherapy-induced nausea and vomiting. It blocks the action of serotonin, a natural substance that may cause nausea and vomiting.
Dosage for Adults – IV- A single 0.25 mg dose is administered over 30 seconds.
It comes as a solution for injection to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of heart disease, decrease in blood minerals, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
• It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
• Most Common :
Headache, constipation, diarrhea, dizziness, fatigue, abdominal pain and sleeplessness.
• Heart : Fast heart rate, slow heart rate, low or high blood pressure, abnormal heart rhythm and heart attack.
• Skin : Skin inflammation and rash.
• Eye and ENT : Motion sickness, ringing in the ear, eye irritation and vision abnormality.
• Gastrointestinal : Indigestion, dry mouth, hiccups and flatulence.
• General : Weakness, fever, hot flash and flu-like syndrome.
• Liver : Increase in liver enzymes level.
• Metabolic : Increase in blood minerals and sugar, loss of appetite and acidity.
• Musculoskeletal : Joint pain.
• Central Nervous System : Drowsiness, sedation, tingling, anxiety and emotions.
• Genitourinary : Urinary retention.
Avoid excess dosage.
Store it at controlled temperature (20-25°C). Protect from light.
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