Norethindrone - Indications, Dosage, Side Effects and Precautions


Information about Norethindrone

Generic Name : Norethindrone
Up-to-date prescription details regarding Norethindrone are provided here.

Pronunciation : nor-ETH-in-drone

Learn the correct pronunciation of the Norethindrone, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y42.4 Therapeutic Classification : Oral Contraceptives

Trade Names/Brand Names of Norethindrone

India :

International :

Ortho Micronor , Aygestin , Nor-QD

Why is Norethindrone Prescribed? (Indications)

This medication is synthetic oral progestin, used for the treatment of secondary amenorrhea (absence of periods for a few months but patient is not pregnant), endometriosis (the tissue that lines the inner wall of the uterus is found at other sites), and abnormal uterine bleeding due to hormonal imbalance. It induces secretory changes in the endometrium. It works by altering the lining of the uterus.

When should Norethindrone not be taken? (Contraindications)

Contraindicated in patients with severe liver dysfunction, undiagnosed vaginal bleeding, porphyria, pregnancy, previous or current blood clot, deep vein thrombosis, and hypersensitivity.

What is the dosage of Norethindrone?

Adult: Oral- The recommended usual dose is 2.5 to 10 mg/day, for 5 to 10 day during the second half of the menstrual period. Endometriosis- 5mg/day for 14days, Max: 15mg/day for 6 to 9 months.

How should Norethindrone be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Norethindrone?

•Caution needed for patients with history of high blood pressure, heart disease, liver impairment, epilepsy, breastfeeding, new onset of migraine-type headache, asthma, kidney impairment, history of clinical depression.

What are the side effects of Norethindrone?

Most Common- Headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps/bloating, nausea and vomiting, hair loss.
Genitourinary- Change in sexual interest, changes in menstrual flow, changes in cervical mucus secretion.
Central Nervous System- Headache, dizziness, mood swings, trouble sleeping.
Heart- High blood pressure Liver- Abnormal liver tests, jaundice.
Eye- Blurred/double vision, loss of vision.
Skin- Hives, rash, acne, growth of hair on face, increased pigmentation.
Metabolic- Increase in blood sugar, increased lipids.
Blood- Increase in blood clots in veins.

What are the other precautions for Norethindrone?

Do not smoke while taking this medication.

What are the storage conditions for Norethindrone?

Oral: Keep this medication in an airtight container, and away from children. Store it at room temperature (below 25°C).