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Nevirapine - Indications, Dosage, Side Effects and Precautions

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Information about Nevirapine

Generic Name : Nevirapine
Up-to-date prescription details regarding Nevirapine are provided here.

Pronunciation : ne- vye'- ra- peen

Learn the correct pronunciation of the Nevirapine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y41.5 Therapeutic Classification : Antivirals

Trade Names/Brand Names of Nevirapine

India :

International :


Viramune.

Why is Nevirapine Prescribed? (Indications)

This medication is a reverse transcriptase inhibitor, prescribed for HIV infection and AIDS. It inhibits the activity of reverse transcriptase enzyme and blocks the production of DNA and new viruses.

When should Nevirapine not be taken? (Contraindications)

Hypersensitivity and in patients with severe liver impairment.

What is the dosage of Nevirapine?

Adult: PO- Combined with other antiretrovirals: The recommended dose is 200 mg once daily for the first 14 days; up to 200 mg twice daily if rash does not develop. Re-introduce at a lower dose for the first 14 days if the treatment is interrupted for >7 days.

How should Nevirapine be taken?

It comes as a tablet, to take by mouth, with or without food.

What are the warnings and precautions for Nevirapine?

• Caution should be exercised in patients with history of kidney disease, liver impairment, during pregnancy and breastfeeding.

• Patient may develop with increased risk of liver damage, serious life threatening allergic reactions, if it is so consult with your doctor.

• It may affect the effectiveness of oral contraceptives; consult with your doctor for other methods to prevent pregnancy while taking this medication.

• It may lead to redistribution/accumulation of body fat in many parts of body.

What are the side effects of Nevirapine?

Body as whole- Swelling in the hand, feet, ankle and lower leg regions, fever and weight loss.
Skin- Rash
Gastrointestinal - Nausea, vomiting, diarrhea and abdominal pain.
Central Nervous System - Headache, fatigue, dizziness and depression.
Musculoskeletal - Muscle pain.
Respiratory - Dry cough.
Metabolic - Increase in liver enzymes.
Potentially Fatal: Severe and life-threatening liver toxicity and skin reactions.

What are the other precautions for Nevirapine?

It may reduce the effectiveness of contraceptives.
Avoid alcoholic beverages.

What are the storage conditions for Nevirapine?

Oral: Store it at 15-30°C, and in an airtight container, keep away from children and light.
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