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General Information on Naproxen and Esomeprazole Magnesium

Generic Name : Naproxen and Esomeprazole Magnesium

Pronunciation : na-PROX-en- ES-oh-MEP-ra-zole

Latest prescription information about Naproxen and Esomeprazole Magnesium. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Naproxen and Esomeprazole Magnesium

International- Vimovo.

Why is Naproxen and Esomeprazole Magnesium Prescribed? (Indications)

This combination medication contains NSAID and a proton pump inhibitor (PPI), prescribed for rheumatoid arthritis, osteoarthritis, or ankylosing spondylitis.  It is used for patients who have an increased risk for stomach ulcers and who need to take a nonsteroidal anti-inflammatory drug (NSAID).

When should Naproxen and Esomeprazole Magnesium not to be taken? (Contraindications)

Contraindicated in patients who have experienced asthma, hives, or allergic-type reactions after taking aspirin or other NSAIDs, perioperative pain, last 3 months of pregnancy, severe liver problem, had bypass heart surgery, and known hypersensitivity.

What is the dosage of Naproxen and Esomeprazole Magnesium?

The recommended dose is one tablet twice daily (375/20mg).

How should Naproxen and Esomeprazole Magnesium be taken?

It comes as a tablet to take by mouth, at least 30 minutes before meals.

What are the warnings and precautions for Naproxen and Esomeprazole Magnesium?

Caution should be exercised in patients with history of kidney or liver disease, diabetes, inflammatory bowel disease, helicobacter pylori infection, stomach problems, high blood pressure, blood disorders, high blood cholesterol, bleeding problems, dehydration, decrease or increase in blood minerals, who are taking low-salt (sodium), alcoholism, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.

It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

Avoid alcohol consumption.

It should not be used in children.

Monitor liver and kidney function, complete blood cell counts, and blood pressure regularly while taking this medication.

What are the side effects of Naproxen and Esomeprazole Magnesium?

   Gastrointestinal : Stomach ulcer, indigestion, stomach inflammation, diarrhea, gastric ulcer, abdominal pain, nausea, hiatus hernia, abdominal distension, flatulence, constipation, stomach bleeding, gastroesophageal reflux disease, duodenal ulcer.
   Infections : Upper respiratory tract infection, lung inflammation, urinary tract infection, sinus inflammation.
   Musculoskeletal : Joint pain.
   Central Nervous System : Headache, abnormal taste.
   Respiratory : Cough.
   Body as a Whole : Anaphylactic reactions, menstrual disorders, chills and fever.
   Heart : Congestive heart failure, inflammation of blood vessels, high blood pressure, lung swelling.
   Liver : Jaundice, abnormal liver function tests.
   Blood : Eosinophilia, anemia, blood in stool, decrease in white blood in stool and platelets.
   Metabolic : Increase or decrease in blood sugar.
   Central Nervous System : Inability to concentrate, depression, dream abnormalities, sleeplessness, uneasiness, muscle pain, muscle weakness, brain inflammation, brain dysfunction, convulsions.
   Respiratory : Asthma.
   Skin : Hair loss, hives, skin rashes, skin death, redness.
   Eye and ENT : Hearing impairment, eye inflammation.
   Genitourinary : Kidney inflammation, blood in urine, kidney failure, female- infertility.

What are the other precautions for Naproxen and Esomeprazole Magnesium?

Avoid excess dosage.

What are the storage conditions for Naproxen and Esomeprazole Magnesium?

Store the medication as directed by your physician.

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