Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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General Information on Methylphenidate

Generic Name : Methylphenidate

Pronunciation : meth ill fen' i date

Latest prescription information about Methylphenidate. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y50.8 | Therapeutic Classification : Cerebral Stimulants

Trade Names/Brand Names of Methylphenidate

India- Addwize, Inspiral.
International- Daytrana.

Why is Methylphenidate Prescribed? (Indications)

This medication is a central nervous system stimulant, prescribed for attention deficit disorder (ADD) and daytime sleep (narcolepsy).  It works by changing the amounts of certain natural substances in the brain.

When should Methylphenidate not to be taken? (Contraindications)

Contraindicated in patients with increased eye pressure, tics, anxiety, tension, agitation, along with MAOIs or within 14 days of treatment with MAOIS, and hypersensitivity.

What is the dosage of Methylphenidate?

PO- ADD- Child- 0.25mg/kg/day. Adult: 5 10mg/day.
Adult: PO- Narcolepsy- 20-30 mg/day in divided doses. Effective range: 10-60 mg/day.

How should Methylphenidate be taken?

It comes as a tablet to take by mouth either on an empty stomach or with food as directed by your physician.

What are the warnings and precautions for Methylphenidate?

Caution should be exercised in patients with history of high blood pressure, heart disease, seizures, overactive thyroid, chronic fatigue, cystic fibrosis, stomach problem, mental disorders, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

It may cause serious side effects such as heart attack, stroke, and sudden death in heart patients. Consult with your doctor before taking this medication.

Monitor blood pressure, heart function, complete blood cell counts regularly while taking this medication.

It should not be used in children less than 6 years.

What are the side effects of Methylphenidate?

   Most Common : Nervousness, difficulty in sleeping, skin rash, loss of appetite, dizziness, drowsiness, palpitations, fever, sore throat, unusual bleeding or bruising.
   Heart : Chest pain, abnormal heart rhythm, palpitations, high/low blood pressure and increased or decreased pulse rate.
   Gastrointestinal : Abdominal pain and nausea.
   Hypersensitivity reactions : Skin inflammation, hives, fever and joint pain.
   Metabolic : Weight loss during prolonged therapy.
   Central Nervous System : Movement disorder, headache and depression.
   Blood : Decrease in white blood cells and anemia.
   Skin : Hair loss.

What are the other precautions for Methylphenidate?

Avoid excess dosage.

What are the storage conditions for Methylphenidate?

Store it at room temperature (25C), away from heat and light.

Schedule : X

Narcotic and Psychotropic drugs which cannot be sold without the prescription of a Registered Medical Practitioner.

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Suraj Bhattarai, Nepal

I need this medicine as prescribed by the doctor in Nepal. But unavailability of this medicine in Nepal and bordering areas of Nepal and India is really hurting me. I've tried to acquire from my relatives in India but couldn't find till date. Ive been asked to tell the manufacturers name which still unknown to us. Could you please help me on this regard where I acquire this? Also the other trade name if any of methylphenidate except Retalin.

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