Medroxyprogesterone - Indications, Dosage, Side Effects and Precautions


Information about Medroxyprogesterone

Generic Name : Medroxyprogesterone
Up-to-date prescription details regarding Medroxyprogesterone are provided here.

Pronunciation : me drox, ee proe jess' te rone

Learn the correct pronunciation of the Medroxyprogesterone, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y42 Therapeutic Classification : Hormones

Trade Names/Brand Names of Medroxyprogesterone

India :

International :

Amen, Curretab, Cycrin, Prodroxy, Provera

Why is Medroxyprogesterone Prescribed? (Indications)

This medication is a progestin hormone, prescribed for menstrual problems, breast cancer and prevention of pregnancy. It stops the growth of the lining of the uterus and induces the uterus to produce certain hormones.

When should Medroxyprogesterone not be taken? (Contraindications)

Contraindicated in patients with known or suspected pregnancy, breast cancer, liver disease and hypersensitivity.

What is the dosage of Medroxyprogesterone?

PO- The recommended dose is 5 to 20 mg.
IM- 50 – 150mg at 1 – 3 month interval.

How should Medroxyprogesterone be taken?

It comes as a tablet to take by mouth, with or without food.
It also comes as a solution for injection to be administered by a healthcare provider into the large muscle.

What are the warnings and precautions for Medroxyprogesterone?

• Caution should be exercised in patients with history of breast cancer, unexplained vaginal bleeding, abortion, blood clot events, stroke, seizures, migraine, headaches, depression, asthma, diabetes, heart, kidney, or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

• Avoid exposure to sunlight; otherwise it may cause dark skin patches.

• It may affect blood sugar level; monitor sugar level regularly.

What are the side effects of Medroxyprogesterone?

Body as a Whole - Headache, abdominal pain/discomfort, fatigue, backache, painful menstruation and hot flashes.
Metabolic - Increased weight.
Central Nervous System - Nervousness, dizziness, decreased libdio, paralysis, facial palsy, tingling and drowsiness.
Genitourinary - Menstrual irregularities, excess bleeding, breast cancer, unexpected pregnancy, vaginal cyst, infections, increased sexual activity and absence of menstrual cycle.
Heart - Fainting, fast heart rate, deep vein thrombosis, pulmonary embolus and varicose veins.
Gastrointestinal - Changes in appetite, jaundice, excessive thirst and rectal bleeding.
Blood - Anemia and blood disorders.
Musculoskeletal - Joint inflammation.
Respiratory - Difficulty in breathing and asthma.
Skin - Excessive sweating, body odor and dry skin.

What are the other precautions for Medroxyprogesterone?

Avoid excess dosage.

What are the storage conditions for Medroxyprogesterone?

Store it at controlled room temperature (20° to 25°C), and in an airtight container.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.