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Medroxyprogesterone - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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General Information on Medroxyprogesterone

Generic Name : Medroxyprogesterone
Pronunciation : me drox, ee proe jess' te rone
Latest prescription information about Medroxyprogesterone. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42 | Therapeutic Classification : Hormones
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Trade Names/Brand Names of Medroxyprogesterone

India : 

More...

International : 

Amen, Curretab, Cycrin, Prodroxy, Provera
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Why is Medroxyprogesterone Prescribed? (Indications)

This medication is a progestin hormone, prescribed for menstrual problems, breast cancer and prevention of pregnancy. It stops the growth of the lining of the uterus and induces the uterus to produce certain hormones.
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When should Medroxyprogesterone not be taken? (Contraindications)

Contraindicated in patients with known or suspected pregnancy, breast cancer, liver disease and hypersensitivity.

What is the dosage of Medroxyprogesterone?

PO- The recommended dose is 5 to 20 mg.
IM- 50 – 150mg at 1 – 3 month interval.

How should Medroxyprogesterone be taken?

It comes as a tablet to take by mouth, with or without food.
It also comes as a solution for injection to be administered by a healthcare provider into the large muscle.

What are the warnings and precautions for Medroxyprogesterone?

• Caution should be exercised in patients with history of breast cancer, unexplained vaginal bleeding, abortion, blood clot events, stroke, seizures, migraine, headaches, depression, asthma, diabetes, heart, kidney, or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

• Avoid exposure to sunlight; otherwise it may cause dark skin patches.

• It may affect blood sugar level; monitor sugar level regularly.

What are the side effects of Medroxyprogesterone?

   Body as a Whole : Headache, abdominal pain/discomfort, fatigue, backache, painful menstruation and hot flashes.
   Metabolic : Increased weight.
   Central Nervous System : Nervousness, dizziness, decreased libdio, paralysis, facial palsy, tingling and drowsiness.
   Genitourinary : Menstrual irregularities, excess bleeding, breast cancer, unexpected pregnancy, vaginal cyst, infections, increased sexual activity and absence of menstrual cycle.
   Heart : Fainting, fast heart rate, deep vein thrombosis, pulmonary embolus and varicose veins.
   Gastrointestinal : Changes in appetite, jaundice, excessive thirst and rectal bleeding.
   Blood : Anemia and blood disorders.
   Musculoskeletal : Joint inflammation.
   Respiratory : Difficulty in breathing and asthma.
   Skin : Excessive sweating, body odor and dry skin.

What are the other precautions for Medroxyprogesterone?

Avoid excess dosage.

What are the storage conditions for Medroxyprogesterone?

Store it at controlled room temperature (20° to 25°C), and in an airtight container.

<>Schedule : HPrescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.



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Comments

arifa, India

this information was very useful

tripti, India

I HAVE TAKEN THREE MONTHS MEPRATE 10 MG. FOR 10 DAYS AFTER HALF OF PERIOD.BUT NOW MY BP. IS GOING UPWARDS WHICH HAS NEVER GONE.I AM FEELING VERY LAZY ALL THE TIME.DOCTOR SUGGESTED PMS. ALL OTHER PROBLEMS ARE SOLVED BUT I DON'T UNDERSTAND I HAVE TO CONTINUE OR NOT.

VAVA WILSON, India

I AM REFERRED FOR IUI NEXT MONTH. I HAD DONE LAPRASCOPY ON 26TH OF AUG. AND I GOT MY REGULAR PERIODS ON 29TH OF AUGUST. I STARTED TAKING MEPRATE ON THE DAY 1 OF PERIOD AS SUGGESTED BY MY DOC. FOR 30 DAYS. THAT IS 29TH OF AUG. TODAY IS 8 TH OF SEPT. 11TH DAY OF MY CYCLE. STILL I HAVE BLEEDING. IS IT BECAUSE OF THAT MEDICINE. WHAT SHALL I DO

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