Lorcaserin is used in adults who are overweight or obese. The drug helps in losing weight.
Lorcaserin may be also used in patients who have weight-related medical problems such as high blood pressure, type 2 diabetes, or high cholesterol level. The weight lost is not regained when taking this drug.
Lorcaserin can be used as add-on therapy when a low - calorie diet and increased physical activity is prescribed for weight management in anyone with a body mass index of over 27 kg/m2 or above in overweight people or 35 kg/m2 in obese people.
Lorcaserin works by interacting with certain chemicals in the brain resulting in increasing the feeling of fullness, thereby consumption of food is reduced.
Lorcaserin should not be used in-
End-stage kidney disease
Children below 18 years of age
Take extra caution in breastfeeding mothers and patients with the severe liver disease.
The recommended dose of lorcaserin is 10 mg twice daily.
No dose modification is required while giving lorcaserin to patients with mild liver or kidney disease.
Patient must be evaluated for weight loss after 12 weeks. If the patient has not lost at least 5% of weight, then the treatment with lorcaserin must be discontinued.
It comes as a tablet to take by mouth, with or without food.
Caution should be exercised in patients with history of heart (congestive heart failure, slow heart beat or heart block), kidney or liver disease, diabetes, sickle cell anemia, multiple myeloma, or leukemia, Peyronies disease, deformed penis, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Most Common :
Headache, depression and dizziness.
Heart : High blood pressure.
Gastrointestinal : Nausea, diarrhea, constipation, dry mouth, vomiting, toothache.
General : Fatigue, swelling in the extremities.
Immune System : Upper respiratory tract infection, throat inflammation, seasonal allergy, urinary tract infection, stomach flu.
Metabolic : Decrease in blood sugar, worsening of diabetes mellitus, decreased appetite.
Musculoskeletal : Back pain, muscles and joint pain.
Central Nervous System : Headache, dizziness, anxiety, sleeplessness, stress and depression.
Respiratory : Cough, throat pain, nose block.
Skin : Rash.
Avoid excess dosage.
Store at 25°C.
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