This medication is a recombinant human granulocyte-colony stimulating factor (G-CSF) used to reduce the risk of life-threatening infection in patients with neutropenia, particularly after cytotoxic chemotherapy.
Contraindicated in patients with bone marrow cancer, children less than 2 years, and hypersensitivity.
IV- Neutropenia: The recommended dose is 150 mcg/m2/day starting from day 2 of transplantation for max of 28 consecutive days.
It comes as a solution for injection, to be administered by a healthcare provider into the vein or under the skin.
• Caution should be exercised in patients with history of bone marrow cancer, sickle-cell anemia, osteoporosis, lung infection, during pregnancy and breastfeeding.
• Monitor complete blood count regularly while taking this medication.
• It may reduce platelet counts; avoid injury or bruising.
• Musculoskeletal :
Musculoskeletal pain, bone pain, splenic enlargement and osteoporosis.
• Gastrointestinal :
Nausea, diarrhea and loss of appetite.
• Blood :
Anemia and decrease in platelet counts.
• Skin :
Painful skin condition, skin death and skin inflammation.
• Miscellaneous :
Fever, headache and painful urination.
Avoid excess dosage.
Store it at room temperature.