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Lapatinib - Indications, Dosage, Side Effects and Precautions

Written by Anushta Chandrapalan, M.Sc  | Medically Checked by S. Hemamalini, B. Pharm
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Information about Lapatinib

Generic Name : Lapatinib
Up-to-date prescription details regarding Lapatinib are provided here.
Pronunciation : la-PA-ti-nib
Learn the correct pronunciation of the Lapatinib, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
ICD Code : Y43.3 | Therapeutic Classification : Chemotherapy
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Trade Names/Brand Names of Lapatinib

International- Tykerb.
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Why is Lapatinib Prescribed? (Indications)

This medication is a protein-tyrosine kinase inhibitor, prescribed for metastatic breast cancer with other medications. It helps stop or slow the spread of cancer cells.
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When should Lapatinib not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Lapatinib?

PO- The recommended dose is 1,250 mg (5 tablets) given orally once daily on days 1-21 continuously in combination with capecitabine 2,000 mg/m2/day.

How should Lapatinib be taken?

It comes as a tablet to take by mouth, at least one hour before, or one hour after food.

What are the warnings and precautions for Lapatinib?

• Caution should be exercised in patients with history of liver, lung, heart disease, irregular heartbeat, low blood electrolyte levels, bone marrow depression, any allergy, children, during pregnancy and breastfeeding.

Monitor liver function, heart function, and complete blood cell counts regularly while taking this medication.

What are the side effects of Lapatinib?

   Gastrointestinal : Diarrhea, mouth ulcer, indigestion, nausea and vomiting.
   Skin : Rash, dry skin, hand and foot syndrome.
   Musculoskeletal : Pain in extremities and back pain.
   Respiratory : Difficulty in breathing.
   Central Nervous System : Sleeplessness.

What are the other precautions for Lapatinib?

Avoid excess dosage.

What are the storage conditions for Lapatinib?

Store it at room temperature (25�C).
Last Updated : August 11, 2022
Learn more about Lapatinib's interaction with Food and Herbs



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WangBC, China

How to buy Lapatinib from China? Thanks a lot!

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