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Infliximab - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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General Information on Infliximab

Generic Name : Infliximab
Pronunciation : in flix' i mab
Latest prescription information about Infliximab. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y45.4 | Therapeutic Classification : Antirheumatics
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Trade Names/Brand Names of Infliximab

India : 

International : 

Remicade
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Why is Infliximab Prescribed? (Indications)

This medication is a monoclonal antibody, prescribed for autoimmune disorders, joint pain, Crohn's disease, inflammatory bowel disease, ankylosing spondylitis, psoriasis.  It blocks the action of TNF-alpha, a substance in the body that causes inflammation.

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When should Infliximab not be taken? (Contraindications)

Allergic to any components of the product, patients with moderate to severe heart failure should not receive more than 5 mg/kg.

What is the dosage of Infliximab?

It is administered intravenously in a dose of 5 mg/kg on day 1, second week, sixth week, and then after every 6 weeks.

How should Infliximab be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Infliximab?

• Avoid vaccination while taking this medication.

• Caution should be exercised in patients with history of hepatitis B.

• It may develop an active infection while using this medication.

What are the side effects of Infliximab?

Gastrointestinal: Stomach pain, nausea, loss of appetite and blood in stool.
  Heart: Chest pain and shortness of breath.
  Miscellaneous: Headache, runny nose, vaginal itching, flushing, rash, joint pain and seizures.

What are the other precautions for Infliximab?

It may affect blood clots, avoid unusual bruising or bleeding.

What are the storage conditions for Infliximab?

Store vials (powder for injection) in refrigerator (36° to 46°F). Do not freeze.




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Comments

jrdick, Canada

I can't find the price of remicade on this site

Parvesh093, India

hi sir me Parvesh kumar and i am illness with ankylosing spondilities about 9 years. my treatment is continuing A.I.I.M.S. and no relief. so
doctor suggestion injection infliximob .
Kindly give your suggestion about my illness if i became perfectely all right yes &no
PARVESH KUMAR

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