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General Information on Ibritumomab Tiuxetan

Generic Name : Ibritumomab Tiuxetan

Pronunciation : EYE-bri-TOOM-oh-mab tye-UX-e-tan/IN-dee-um

Latest prescription information about Ibritumomab Tiuxetan. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.3 | Therapeutic Classification : Chemotherapy

Trade Names/Brand Names of Ibritumomab Tiuxetan

International- Zevalin Kit-Indium-111.

Why is Ibritumomab Tiuxetan Prescribed? (Indications)

This medication is a monoclonal antibody, prescribed for non-Hodgkin's lymphoma with other medications. It works by killing certain blood and cancer cells from body immune system.

When should Ibritumomab Tiuxetan not to be taken? (Contraindications)

Contraindicated in patients with bone marrow depression and hypersensitivity.

What is the dosage of Ibritumomab Tiuxetan?

Adults- IV- Step 1: Infuse rituximab 250 mg/m 2 at a rate of 50 mg/h, escalate the dose up to 400mg/hr. After this administer indium-111 (In-111) ibritumomab tiuxetan 5 mCi (1.6 mg total antibody dose) administered as a 10-min IV push.
Step 2: Continue this procedure for 7 to 9 days.

How should Ibritumomab Tiuxetan be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Ibritumomab Tiuxetan?

Caution should be exercised in patients with history of blood disorders, decrease in complete blood cell counts due to bone marrow depression, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause dizziness, do not drive a car or operate machinery while taking this medication.

It may reduce platelet counts; avoid injury or bruising.

Avoid contact with people who have infections.

Patient may develop with increased the risk of certain blood cancers; consult with your doctor before taking this medication.

Avoid live vaccination during the treatment period.

Monitor complete blood counts regularly while taking this medication.

What are the side effects of Ibritumomab Tiuxetan?

   Most Common : Reduction in the number of blood cells, fatigue, abdominal pain, nausea, cold, weakness, diarrhea, cough and fever.
   Body as a Whole : Influenza-like illness.
   Musculoskeletal : Muscle pain and loss of appetite.
   Respiratory : Cough, throat pain, upper respiratory tract infection and nosebleed.
   Central Nervous System : Dizziness.
   Heart : High blood pressure.
   Skin : Night sweats, blister, itching and rash.
   Genitourinary : Urinary tract infection.

What are the other precautions for Ibritumomab Tiuxetan?

Avoid excess dosage.

What are the storage conditions for Ibritumomab Tiuxetan?

Store it in refrigerator (2-8C). Do not freeze.

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