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Guaifenesin - Indications, Dosage, Side Effects and Precautions

Last Updated on May 11, 2020
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Information about Guaifenesin

Generic Name : Guaifenesin
Pronunciation : gwye fen' e sin
Latest prescription information about Guaifenesin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y55.4 | Therapeutic Classification : Expectorant and Cough Products

Trade Names/Brand Names of Guaifenesin

India : 


International : 

Barkeit Tab, Capex-Bron Exp, Robitussin Ac, Entex La, Organidin NR

Other Name(s) of Guaifenesin

Glyceryl Guaiacolate

Why is Guaifenesin Prescribed? (Indications)

This medication is an expectorant, prescribed for chest congestion. It promotes lower respiratory tract drainage by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways.  


When should Guaifenesin not be taken? (Contraindications)


What is the dosage of Guaifenesin?

PO- The recommended dose is 200 to 400 mg 4 hourly. Max: 2.4 g/day.

How should Guaifenesin be taken?

It comes as tablets, capsules, granules and syrup, to take orally with or without food as directed by your physician.

What are the warnings and precautions for Guaifenesin?

• Caution should be exercised in patients with history of persistent cough e.g. occurs with smoking, asthma, chronic bronchitis or emphysema, cough accompanied by excessive secretions, cough with a fever, rash or persistent headache, pregnancy, lactation, porphyria.

What are the side effects of Guaifenesin?

  Central Nervous System: Dizziness and headache.
  Skin: Rash and hives.
  Gastrointestinal: Nausea and vomiting.

What are the other precautions for Guaifenesin?

Avoid abrupt withdrawal, otherwise excessive elevations in blood pressure and symptoms such as nervousness, headache and confusion may occur.

What are the storage conditions for Guaifenesin?

Store it in room temperature and in airtight container. Keep away from children.

Last Updated : 3/8/2023

Guaifenesin : Frequently Asked Questions

Q: How long can Guaifenesin be taken?

A: Guaifenesin is intended for short-term use. Do not take this medication for more than 7 days to treat cold or allergy symptoms (1 Trusted Source
Role of guaifenesin in the management of chronic bronchitis and upper respiratory tract infections

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Q: Is Guaifenesin safe for people with heart disease?

A: Guaifenesin is generally safe for heart patients. This drug is not known to elevate blood pressure. If guaifenesin is taken in overdose, it may have serious negative effects on the heart and raise the heart rate.

Q: What are the available dosage forms of Guaifenesin?

A: Guaifenesin is available as a tablet, a capsule, an extended-release tablet, dissolving granules, and an oral solution (2 Trusted Source

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Q: How should Guaifenesin be taken?

A: The tablets, capsules, dissolving granules, and an oral solution are usually taken with or without food every 4 hours as prescribed. The extended-release tablet is usually taken with or without food every 12 hours (2 Trusted Source

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Q: Is Guaifenesin a safe drug?

A: Guaifenesin is generally considered a safe and effective expectorant for the treatment of mucus-related symptoms in acute upper respiratory tract infections and stable chronic bronchitis (1 Trusted Source
Role of guaifenesin in the management of chronic bronchitis and upper respiratory tract infections

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  • 1. Role of guaifenesin in the management of chronic bronchitis and upper respiratory tract infections - ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724298/ )
  • 2. Guaifenesin - (https://medlineplus.gov/druginfo/meds/a682494.html )
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