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Glycerol Phenylbutyrate - Indications, Dosage, Side Effects and Precautions

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Information about Glycerol Phenylbutyrate

Generic Name : Glycerol Phenylbutyrate
Latest prescription information about Glycerol Phenylbutyrate. Learn its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
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Trade Names/Brand Names of Glycerol Phenylbutyrate

International- Ravicti.
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Why is Glycerol Phenylbutyrate Prescribed? (Indications)

This medication is a nitrogen-binding agent, prescribed for the treatment of Urea Cycle Disorders (UCD) in pediatric patients more than 2 years old and adults.  
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When should Glycerol Phenylbutyrate not be taken? (Contraindications)

It should not be administered to children less than 2 years old and patients with known hypersensitivity.

What is the dosage of Glycerol Phenylbutyrate?

The recommended total daily dosage is given in 3 equally divided dosages, rounded upto nearest 0.5 mL. The maximum total daily dosage is 17.5 mL (19 g).

How should Glycerol Phenylbutyrate be taken?

It comes as oral liquid to take by mouth, with food.

What are the warnings and precautions for Glycerol Phenylbutyrate?

• Caution should be exercised in patients with history of liver or kidney problems, bowel (intestine) problems, any allergy, who are taking other medications, during pregnancy and breastfeeding.

Patient may develop neurotoxicity, if it is so reduce the dosage.

What are the side effects of Glycerol Phenylbutyrate?

   Most Common : Diarrhea, flatulence and headache.
   Gastrointestinal : Abdominal discomfort, abdominal pain, indigestion, nausea, vomiting.
   General : Fatigue.
   Metabolic : Increased ammonia levels, decreased appetite.
   Central Nervous System : Dizziness.

What are the other precautions for Glycerol Phenylbutyrate?

Avoid excess dosage.

What are the storage conditions for Glycerol Phenylbutyrate?

Store it in controlled room temperature (20C to 25C).



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