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General Information on Gilteritinib

Generic Name : Gilteritinib

Pronunciation : gil

Latest prescription information about Gilteritinib. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, warnings and its storage instructions . Also listed are the Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Gilteritinib

XOSPATA

Overview of Gilteritinib

Gilteritinib is an anticancer drug approved for treating adults with relapsed or refractory acute myeloid leukemia (AML).

Why is Gilteritinib Prescribed? (Indications)

Gilteritinib is an anticancer drug approved for treating adults with relapsed or refractory acute myeloid leukemia (AML) with a specific gene (FLT3) mutation.
AML is a type of blood cancer, in which the count of white blood cells increases significantly. 

When should Gilteritinib not to be taken? (Contraindications)

Hypersensitivity to Gilteritinib or any of the excipients.

What is the dosage of Gilteritinib?

It is available as a 40mg tablet.
The initial dose for adults is 120mg once a day orally with or without food.

Missed a Dose?

If a dose of Gilteritinib is missed or not taken at the routine time, it should be taken as soon as possible on the same day.
Two doses should be taken in 12 hours.

How should Gilteritinib be taken?

Do not break or crush Gilteritinib tablets. They should be taken at about the same time each day.

What are the side effects of Gilteritinib?

1. General: Fever, edema, fatigue, eye disorders, joint pains, rash
2. Gastrointestinal: Nausea, vomiting, constipation, diarrhea
3. Nervous system: Dizziness, headache
4. Respiratory: Cough, shortness of breath
5. Vascular: Hypotension
6. Raised liver enzymes, renal impairment

What are the other precautions for Gilteritinib?

Caution is advised for the following group of patients:
1.Posterior reversible encephalopathy syndrome
2.Prolonged QT Interval (an ECG abnormality)
3.Low potassium (Hypokalemia) or low magnesium ( hypomagnesemia)
4.Inflammation of the pancreas (pancreatitis)
5.Embryo-Fetal Toxicity: Giteritinib can cause fetal harm when administered to a pregnant woman. Women should use proper contraception in this case.

What are the Drug Interactions of Gilteritinib?

Gilteritinib will interact with these drugs:
1.Escitalopram
2.Fluoxetine
3.Sertraline

What are the storage conditions for Gilteritinib?

Store Gilteritinib tablets at 20C to 25C.
Keep in the original container until dispensed.
Protect from light, moisture, and humidity.

Last Updated : 2/15/2021

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