Pallavi Singh
Written & Compiled by Pharmacist Pallavi Singh, M. Pharmacy (Pharmacy Practice)
Dr. Simi Paknikar
Medically Reviewed by Dr. Simi Paknikar, MD
Last Updated on Nov 23, 2017
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General Information on Gemifloxacin

Generic Name : Gemifloxacin

Pronunciation : je-mi-FLOKS-a-sin

Latest prescription information about Gemifloxacin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Antibiotics

Overview of Gemifloxacin

Gemifloxacin is a fluoroquinolone antibiotic; it is used for the treatment of bacterial infections.

Why is Gemifloxacin Prescribed? (Indications)

Gemifloxacin is a fluoroquinolone antibiotic. It is used for the treatment of infections like pneumonia and bronchitis. Gemifloxacin kills the bacteria which can cause the infection. 

When should Gemifloxacin not to be taken? (Contraindications)

Gemifloxacin is contraindicated in patients allergic to the drug or to other quinolones.

What is the dosage of Gemifloxacin?

The recommended adult dose of gemifloxacin is 320mg tablet taken orally once a day for five to seven days.

How should Gemifloxacin be taken?

Gemifloxacin should be taken with plenty of water.

What are the warnings and precautions for Gemifloxacin?

The patient should consult the doctor in case of any pain and swelling or inflammation in joints.
Caution should be taken while using it in elderly patients.

What are the side effects of Gemifloxacin?

  Nervous system: Headache and dizziness
  Skin: Skin rash
  Digestive tract: Diarrhea, nausea, abdominal pain and vomiting
  Blood: Increase or decrease in white blood cells or platelets
  Liver: Increase in liver enzymes
  Heart: Prolonged QTc interval on ECG
  Others: Tendonitis, tendon rupture, peripheral neuritis, low blood glucose levels, allergic reactions, photosensitive reactions. Superinfection with Clostridium difficile can occur with prolonged use of the antibiotic

What are the other precautions for Gemifloxacin?

The medication should be avoided in pregnant women
The dose should be reduced in patients with severe kidney disease
Avoid in patients with myasthenia gravis due to possible exacerbation of muscle weakness
Use with caution in patients with rheumatoid arthritis due to increased risk of tendon rupture

What are the Drug Interactions of Gemifloxacin?

Gemifloxacin may increase the chances of bleeding when given with warfarin.
Probenecid may increase the plasma concentration of gemifloxacin.
The absorption of gemifloxacin is reduced when administered with supplements that contain iron, zinc or magnesium. These should be avoided 3 hours before and 2 hours after taking gemifloxacin.
Gemifloxacin may increase the glucose-lowering effect of anti-diabetes drugs.
The risk of tendonitis and tendon rupture may increase when administered with corticosteroids.
The risk of heart rhythm abnormalities due to drugs that prolong QTc interval may increase with concomitant gemifloxacin.
Gemifloxacin may reduce the serum concentration of the active metabolite of mycophenolate.
Quinapril, sucralfate and sevelamer may reduce the concentration of gemifloxacin.

What are the storage conditions for Gemifloxacin?

Gemifloxacin should be stored at 15-30℃ temperature.

Last Updated : 11/23/2017

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