This medication is a tumor-necrosis factor (TNF) blocker, prescribed for ankylosing spondylitis (type of joint pain that affects your back), juvenile arthritis (arthritis-related condition that develops in children), psoriasis, and rheumatoid (inflammation of the joints) and psoriatic arthritis.
Contraindicated in patients with hypersensitivity or widespread infection.
Adult- SC- The recommended dose is 50 mg weekly; twice weekly in plaque psoriasis. 0.8 mg/kg/week in children.
It is administered as an injection just under the skin by a healthcare provider.
Avoid using contaminated solution of this drug or if the appearance of the solution is changed.
Do not have any vaccinations while taking this medication.
It may increase the risk of cancer and serious infections including tuberculosis.
Caution needed in patients with history of decreased bone marrow function, history of cancer (e.g., lymphoma), seizures, active or reoccurring infections, diabetes, certain brain/spinal cord disorders (demyelinating disorders such as multiple sclerosis), blood disorders, heart disease (e.g., heart failure), allergies during pregnancy, in elderly, and children between 2 to 18 yrs.
It should not be used in children less than 2 years.
Do not share this medication with others.
Serious adverse effects:
Increase in serious infections including fungal infections and tuberculosis and cancers like lymphomas.
Heart: Congestive Heart failure, heart attack.
Central Nervous System: Seizures, headache, dizziness, stroke, demyelinating diseases, inflammation of nerves, aseptic meningitis (inflammation of the covering of the brain in the absence of infection), hydrocephalus (abnormal accumulation of cerebrospinal fluid (CSF) within brain).
Skin: Rash, hair loss, worsening psoriasis, inflammation of blood vessels in skin, skin cancer, severe allergic reactions.
Eye and ENT: Inflammation of eyes, nose and throat.
Gastrointestinal: Abdominal pain, nausea, vomiting, stomach upset, altered sense of taste, loss of appetite, diarrhea, dry mouth, inflammation of the digestive system, perforation of the intestine.
Genitourinary: Kidney stone, kidney damage, urinary tract infection.
Blood: Decrease in red blood cells, white blood cells and /or platelets, lymph node swelling.
Liver: Liver inflammation.
Local: Injection-site reactions (erythema and/or itching, pain, or swelling).
Metabolic: Increase in blood sugar, weight gain.
Musculoskeletal: Inflammation of bursa, muscles, joint pain, lupus-like syndrome.
Respiratory: Upper respiratory tract infections, cough, difficulty in breathing, lung disease.
♦ Miscellaneous: Autoimmune reaction, inflammation of veins, flu like syndrome, Sarcoidosis.
If you miss a dose, contact your doctor or pharmacist.
Store at 25Â°C. Store it in airtight container and keep away from children.
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